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    NEK8 NIMA related kinase 8 [ Bos taurus (cattle) ]

    Gene ID: 532332, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NEK8provided by VGNC
    Official Full Name
    NIMA related kinase 8provided by VGNC
    Primary source
    VGNC:VGNC:55860
    See related
    BGD:BT29893; Ensembl:ENSBTAG00000015535
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 19
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (20151458..20164407)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA Z17 Neighboring gene ribosomal protein L23a Neighboring gene TLC domain containing 1 Neighboring gene TNF receptor associated factor 4 Neighboring gene family with sequence similarity 222 member B Neighboring gene transfer RNA glycine (anticodon UCC)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase Nek8
    Names
    NIMA (never in mitosis gene a)- related kinase 8
    NP_001179652.1
    XP_024836013.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192723.1 → NP_001179652.1  serine/threonine-protein kinase Nek8

      See identical proteins and their annotated locations for NP_001179652.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000019
      UniProtKB/TrEMBL
      E1B827
      Related
      ENSBTAP00000020643.7, ENSBTAT00000020643.7
      Conserved Domains (4) summary
      smart00220
      Location:4 → 256
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG5184
      Location:318 → 663
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd08220
      Location:3 → 258
      STKc_Nek8; Catalytic domain of the Protein Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase 8
      pfam00415
      Location:585 → 634
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      20151458..20164407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024980245.2 → XP_024836013.1  serine/threonine-protein kinase Nek8 isoform X1

      UniProtKB/TrEMBL
      E1B827
      Conserved Domains (3) summary
      cd08220
      Location:3 → 258
      STKc_Nek8; Catalytic domain of the Protein Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase 8
      pfam00415
      Location:584 → 633
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      cl27697
      Location:318 → 599
      RCC1; Regulator of chromosome condensation (RCC1) repeat
    Nucleotide Protein Strain
    Heading Accession and Version

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