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    EPS8L1 EPS8 like 1 [ Bos taurus (cattle) ]

    Gene ID: 514504, updated on 5-Mar-2024

    Summary

    Official Symbol
    EPS8L1provided by VGNC
    Official Full Name
    EPS8 like 1provided by VGNC
    Primary source
    VGNC:VGNC:28556
    See related
    BGD:BT18504
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
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    Genomic context

    See EPS8L1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (62311447..62323690, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene troponin T1, slow skeletal type Neighboring gene protein phosphatase 1 regulatory subunit 12C Neighboring gene uncharacterized LOC112442387 Neighboring gene retinol dehydrogenase 13 Neighboring gene uncharacterized LOC100848752

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in positive regulation of ruffle assembly IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in ruffle membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    epidermal growth factor receptor kinase substrate 8-like protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192376.2NP_001179305.1  epidermal growth factor receptor kinase substrate 8-like protein 1

      See identical proteins and their annotated locations for NP_001179305.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000018
      UniProtKB/TrEMBL
      A0A3Q1LWG4, E1BKS0
      Conserved Domains (3) summary
      cd11764
      Location:480532
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:32160
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:657722
      SAM_superfamily; SAM (Sterile alpha motif )

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      62311447..62323690 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059876678.1XP_059732661.1  epidermal growth factor receptor kinase substrate 8-like protein 1 isoform X1