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    Ier3ip1-ps1 immediate early response 3 interacting protein 1, pseudogene 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500270, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Ier3ip1-ps1provided by RGD
    Official Full Name
    immediate early response 3 interacting protein 1, pseudogene 1provided by RGD
    Primary source
    RGD:1561565
    See related
    AllianceGenome:RGD:1561565
    Gene type
    pseudo
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ier3ip1
    Summary
    Predicted to be involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; positive regulation of secretion by cell; and regulation of fibroblast apoptotic process. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be active in COPII-coated ER to Golgi transport vesicle and endoplasmic reticulum membrane. Predicted to be integral component of Golgi membrane. Orthologous to human IER3IP1 (immediate early response 3 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    Location:
    4q34
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (133898662..133899156)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (132342131..132342625)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (132140802..132152059)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene forkhead box P1 Neighboring gene uncharacterized LOC102555037 Neighboring gene eukaryotic translation initiation factor 4E family member 3 Neighboring gene G protein-coupled receptor 27 Neighboring gene prokineticin 2 Neighboring gene uncharacterized LOC120102349

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Microcephaly with simplified gyration, epilepsy, and infantile diabetes linked to inappropriate apoptosis of neural progenitors. Poulton CJ, et al. Am J Hum Genet, 2011 Aug 12. PMID 21835305, Free PMC Article
    2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Other Names

    • immediate early response 3 interacting protein 1 pseudogene

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in brain development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in organ growth ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of extracellular matrix constituent secretion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of protein secretion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of fibroblast apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_115664.1 

      Range
      101..595
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      133898662..133899156
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001047956.2: Suppressed sequence

      Description
      NM_001047956.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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