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    EDN2 endothelin 2 [ Felis catus (domestic cat) ]

    Gene ID: 494215, updated on 5-Mar-2024

    Summary

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    Official Symbol
    EDN2
    Official Full Name
    endothelin 2
    Primary source
    VGNC:VGNC:61727
    See related
    EnsemblRapid:ENSFCTG00005030460
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Felis catus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: C1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) C1 NC_058375.1 (32281256..32286853, complement)
    104 previous assembly Felis_catus_9.0 (GCF_000181335.3) C1 NC_018730.3 (32507439..32513038, complement)

    Chromosome C1 - NC_058375.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111561718 Neighboring gene forkhead box O6 Neighboring gene HIVEP zinc finger 3 Neighboring gene uncharacterized LOC123379581 Neighboring gene 60S ribosomal protein L17-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of preproendothelin-2 splice variant in cat. Uchide T, et al. J Vet Med Sci, 2006 Jan. PMID 16462117

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables endothelin B receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of prostaglandin-endoperoxide synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of systemic arterial blood pressure by endothelin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of vasoconstriction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vein smooth muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    endothelin-2
    Names
    ET-2
    PPET2
    preproendothelin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009387.1 → NP_001009387.1  endothelin-2 precursor

      See identical proteins and their annotated locations for NP_001009387.1

      Status: PROVISIONAL

      Source sequence(s)
      AB197699
      UniProtKB/Swiss-Prot
      Q5NRQ0
      UniProtKB/TrEMBL
      A0A384DV29
      Related
      ENSFCTP00005058001.1, ENSFCTT00005084891.1
      Conserved Domains (2) summary
      smart00272
      Location:95 → 114
      END; Endothelin
      pfam00322
      Location:45 → 73
      Endothelin; Endothelin family

    RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference F.catus_Fca126_mat1.0 Primary Assembly

    Genomic

    1. NC_058375.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

      Range
      32281256..32286853 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5NRQ0.1 GenPept UniProtKB/Swiss-Prot:Q5NRQ0

    Gene LinkOut

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