DPYSL4 dihydropyrimidinase like 4 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: DPYSL4provided by VGNC
Official Full Name: dihydropyrimidinase like 4provided by VGNC
Primary source: VGNC:VGNC:49877
See related: Ensembl:ENSCAFG00845023871
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 28

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	28	NC_051832.1 (40816840..40831202)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	28	NC_006610.4 (40235701..40250040)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	28	NC_049249.1 (40687937..40702309)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	28	NC_049288.1 (40300771..40315112)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	28	NC_049769.1 (40288656..40302623)

Chromosome 28 - NC_051832.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dihydropyrimidinase-related protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051832.1 Reference ROS_Cfam_1.0

Range

40816840..40831202

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038440982.1 → XP_038296910.1 dihydropyrimidinase-related protein 4 isoform X1

UniProtKB/TrEMBL

A0A8C0MNV8

Conserved Domains (1) summary

cd01314
Location:22 → 471

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...
XM_038440984.1 → XP_038296912.1 dihydropyrimidinase-related protein 4 isoform X2

UniProtKB/TrEMBL

A0A8C0MIW8, A0A8C0MNV8, A0A8I3S7T3

Related

ENSCAFP00845033090.1, ENSCAFT00845042190.1

Conserved Domains (1) summary

cd01314
Location:17 → 466

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049288.1 Alternate UMICH_Zoey_3.1

Range

40300771..40315112

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038515560.1 → XP_038371488.1 dihydropyrimidinase-related protein 4 isoform X1

Conserved Domains (1) summary

cd01314
Location:22 → 471

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...
XM_038515562.1 → XP_038371490.1 dihydropyrimidinase-related protein 4 isoform X3
XM_038515561.1 → XP_038371489.1 dihydropyrimidinase-related protein 4 isoform X2

Conserved Domains (1) summary

cd01314
Location:17 → 466

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...
XM_038515563.1 → XP_038371491.1 dihydropyrimidinase-related protein 4 isoform X3

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049769.1 Alternate UNSW_CanFamBas_1.0

Range

40288656..40302623

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038643399.1 → XP_038499327.1 dihydropyrimidinase-related protein 4 isoform X1

Conserved Domains (1) summary

cd01314
Location:22 → 471

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...
XM_038643401.1 → XP_038499329.1 dihydropyrimidinase-related protein 4 isoform X4
XM_038643400.1 → XP_038499328.1 dihydropyrimidinase-related protein 4 isoform X2

Conserved Domains (1) summary

cd01314
Location:17 → 466

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...
XM_038643402.1 → XP_038499330.1 dihydropyrimidinase-related protein 4 isoform X4

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049249.1 Alternate UU_Cfam_GSD_1.0

Range

40687937..40702309

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038579170.1 → XP_038435098.1 dihydropyrimidinase-related protein 4 isoform X1

UniProtKB/TrEMBL

A0A8C0MNV8

Conserved Domains (1) summary

cd01314
Location:22 → 471

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...
XM_038579171.1 → XP_038435099.1 dihydropyrimidinase-related protein 4 isoform X2

UniProtKB/TrEMBL

A0A8C0MIW8, A0A8C0MNV8, A0A8I3S7T3

Conserved Domains (1) summary

cd01314
Location:17 → 466

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006610.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

40235701..40250040

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_022411761.1 → XP_022267469.1 dihydropyrimidinase-related protein 4 isoform X1

UniProtKB/TrEMBL

A0A8C0MNV8

Conserved Domains (1) summary

cd01314
Location:22 → 471

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...
XM_038460520.1 → XP_038316448.1 dihydropyrimidinase-related protein 4 isoform X2

UniProtKB/TrEMBL

A0A8C0MIW8, A0A8C0MNV8, A0A8I3S7T3

Conserved Domains (1) summary

cd01314
Location:17 → 466

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...