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    NLRP1 NLR family pyrin domain containing 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 489449, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NLRP1provided by VGNC
    Official Full Name
    NLR family pyrin domain containing 1provided by VGNC
    Primary source
    VGNC:VGNC:43845
    See related
    Ensembl:ENSCAFG00845002510
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (31369269..31407109)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (31399983..31440503)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (31467813..31507973)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (31334819..31372650)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (31293857..31331580)

    Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119871754 Neighboring gene uncharacterized LOC119872009 Neighboring gene atherin Neighboring gene MIS12 kinetochore complex component

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of canonical inflammasome complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NACHT, LRR and PYD domains-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051809.1 Reference ROS_Cfam_1.0

      Range
      31369269..31407109
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038665187.1 → XP_038521115.1  NACHT, LRR and PYD domains-containing protein 1 isoform X7

      Conserved Domains (6) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    2. XM_038665188.1 → XP_038521116.1  NACHT, LRR and PYD domains-containing protein 1 isoform X8

      Conserved Domains (8) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:742 → 755
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam13553
      Location:1050 → 1133
      FIIND; Function to find
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    3. XM_038665186.1 → XP_038521114.1  NACHT, LRR and PYD domains-containing protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0PVX3
      Conserved Domains (8) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:742 → 755
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam13553
      Location:1050 → 1305
      FIIND; Function to find
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    4. XM_038665183.1 → XP_038521111.1  NACHT, LRR and PYD domains-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PVX3
      Conserved Domains (9) summary
      PHA03377
      Location:86 → 240
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      cd08330
      Location:1326 → 1406
      CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins
      sd00033
      Location:787 → 815
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:741 → 754
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:299 → 467
      NACHT; NACHT domain
      pfam13553
      Location:1049 → 1306
      FIIND; Function to find
      pfam17779
      Location:537 → 583
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:644 → 936
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    5. XM_038665181.1 → XP_038521109.1  NACHT, LRR and PYD domains-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PVX3
      Conserved Domains (9) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      cd08330
      Location:1327 → 1407
      CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:742 → 755
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam13553
      Location:1050 → 1307
      FIIND; Function to find
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    6. XM_038665185.1 → XP_038521113.1  NACHT, LRR and PYD domains-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8C0PVX3
      Conserved Domains (9) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      cd08330
      Location:1280 → 1360
      CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:742 → 755
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam13553
      Location:1050 → 1260
      FIIND; Function to find
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    7. XM_038665182.1 → XP_038521110.1  NACHT, LRR and PYD domains-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0PVX3
      Conserved Domains (9) summary
      PHA03377
      Location:86 → 240
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      cd08330
      Location:1326 → 1406
      CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins
      sd00033
      Location:787 → 815
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:741 → 754
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:299 → 467
      NACHT; NACHT domain
      pfam13553
      Location:1049 → 1306
      FIIND; Function to find
      pfam17779
      Location:537 → 583
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:644 → 936
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    8. XM_038665184.1 → XP_038521112.1  NACHT, LRR and PYD domains-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0PVX3, A0A8I3MJ75
      Related
      ENSCAFP00845003539.1, ENSCAFT00845004425.1
      Conserved Domains (9) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      cd08330
      Location:1322 → 1402
      CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:742 → 755
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam13553
      Location:1050 → 1302
      FIIND; Function to find
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    RNA

    1. XR_005427036.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049265.1 Alternate UMICH_Zoey_3.1

      Range
      31334819..31372650
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038475293.1 → XP_038331221.1  NACHT, LRR and PYD domains-containing protein 1 isoform X7

    2. XM_038475294.1 → XP_038331222.1  NACHT, LRR and PYD domains-containing protein 1 isoform X8

    3. XM_038475292.1 → XP_038331220.1  NACHT, LRR and PYD domains-containing protein 1 isoform X6

    4. XM_038475291.1 → XP_038331219.1  NACHT, LRR and PYD domains-containing protein 1 isoform X5

    5. XM_038475289.1 → XP_038331217.1  NACHT, LRR and PYD domains-containing protein 1 isoform X3

    6. XM_038475287.1 → XP_038331215.1  NACHT, LRR and PYD domains-containing protein 1 isoform X1

    7. XM_038475288.1 → XP_038331216.1  NACHT, LRR and PYD domains-containing protein 1 isoform X2

    8. XM_038475290.1 → XP_038331218.1  NACHT, LRR and PYD domains-containing protein 1 isoform X4

    RNA

    1. XR_005325561.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

      Range
      31293857..31331580
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038600661.1 → XP_038456589.1  NACHT, LRR and PYD domains-containing protein 1 isoform X7

    2. XM_038600662.1 → XP_038456590.1  NACHT, LRR and PYD domains-containing protein 1 isoform X8

    3. XM_038600660.1 → XP_038456588.1  NACHT, LRR and PYD domains-containing protein 1 isoform X6

    4. XM_038600659.1 → XP_038456587.1  NACHT, LRR and PYD domains-containing protein 1 isoform X5

    5. XM_038600657.1 → XP_038456585.1  NACHT, LRR and PYD domains-containing protein 1 isoform X3

    6. XM_038600655.1 → XP_038456583.1  NACHT, LRR and PYD domains-containing protein 1 isoform X1

    7. XM_038600656.1 → XP_038456584.1  NACHT, LRR and PYD domains-containing protein 1 isoform X2

    8. XM_038600658.1 → XP_038456586.1  NACHT, LRR and PYD domains-containing protein 1 isoform X4

    RNA

    1. XR_005393980.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

      Range
      31467813..31507973
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038536463.1 → XP_038392391.1  NACHT, LRR and PYD domains-containing protein 1 isoform X7

    2. XM_038536464.1 → XP_038392392.1  NACHT, LRR and PYD domains-containing protein 1 isoform X8

    3. XM_038536462.1 → XP_038392390.1  NACHT, LRR and PYD domains-containing protein 1 isoform X11

      UniProtKB/TrEMBL
      A0A8C0PVX3

    4. XM_038536461.1 → XP_038392389.1  NACHT, LRR and PYD domains-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8C0PVX3

    5. XM_038536459.1 → XP_038392387.1  NACHT, LRR and PYD domains-containing protein 1 isoform X9

      UniProtKB/TrEMBL
      A0A8C0PVX3

    6. XM_038536460.1 → XP_038392388.1  NACHT, LRR and PYD domains-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A8C0PVX3

    7. XM_038536458.1 → XP_038392386.1  NACHT, LRR and PYD domains-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0PVX3

    RNA

    1. XR_005359433.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      31399983..31440503
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038513370.1 → XP_038369298.1  NACHT, LRR and PYD domains-containing protein 1 isoform X7

      Conserved Domains (7) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:742 → 755
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    2. XM_005619883.4 → XP_005619940.2  NACHT, LRR and PYD domains-containing protein 1 isoform X8

      Conserved Domains (8) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:742 → 755
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam13553
      Location:1050 → 1133
      FIIND; Function to find
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    3. XM_038513361.1 → XP_038369289.1  NACHT, LRR and PYD domains-containing protein 1 isoform X14

      UniProtKB/TrEMBL
      A0A8C0PVX3
      Conserved Domains (8) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:742 → 755
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam13553
      Location:1050 → 1300
      FIIND; Function to find
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    4. XM_038513352.1 → XP_038369280.1  NACHT, LRR and PYD domains-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8C0PVX3
      Conserved Domains (9) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      cd08330
      Location:1280 → 1360
      CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:742 → 755
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam13553
      Location:1050 → 1260
      FIIND; Function to find
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    5. XM_005619881.4 → XP_005619938.2  NACHT, LRR and PYD domains-containing protein 1 isoform X12

      UniProtKB/TrEMBL
      A0A8C0PVX3
      Conserved Domains (9) summary
      PHA03377
      Location:86 → 240
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      cd08330
      Location:1321 → 1401
      CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins
      sd00033
      Location:787 → 815
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:741 → 754
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:299 → 467
      NACHT; NACHT domain
      pfam13553
      Location:1049 → 1301
      FIIND; Function to find
      pfam17779
      Location:537 → 583
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:644 → 936
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    6. XM_038513349.1 → XP_038369277.1  NACHT, LRR and PYD domains-containing protein 1 isoform X13

      UniProtKB/TrEMBL
      A0A8C0PVX3
      Conserved Domains (9) summary
      PHA03377
      Location:86 → 240
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      cd08330
      Location:1321 → 1401
      CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins
      sd00033
      Location:787 → 815
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:741 → 754
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:299 → 467
      NACHT; NACHT domain
      pfam13553
      Location:1049 → 1301
      FIIND; Function to find
      pfam17779
      Location:537 → 583
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:644 → 936
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    7. XM_005619880.4 → XP_005619937.2  NACHT, LRR and PYD domains-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0PVX3, A0A8P0NH38
      Conserved Domains (9) summary
      PHA03377
      Location:86 → 241
      PHA03377; EBNA-3C; Provisional
      cd08320
      Location:9 → 89
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      cd08330
      Location:1322 → 1402
      CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins
      sd00033
      Location:788 → 816
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:742 → 755
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:300 → 468
      NACHT; NACHT domain
      pfam13553
      Location:1050 → 1302
      FIIND; Function to find
      pfam17779
      Location:538 → 584
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:645 → 937
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    RNA

    1. XR_005346184.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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