PDXK pyridoxal kinase [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: PDXKprovided by VGNC
Official Full Name: pyridoxal kinaseprovided by VGNC
Primary source: VGNC:VGNC:49939
See related: Ensembl:ENSCAFG00845018299
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 31

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	31	NC_051835.1 (37225468..37251568)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	31	NC_006613.4 (36836971..36865273)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	31	NC_049252.1 (37571216..37599584)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	31	NC_049291.1 (37093275..37121572)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	31	NC_049772.1 (37079116..37107424)

Chromosome 31 - NC_051835.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables pyridoxal kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in pyridoxal 5'-phosphate salvage	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: pyridoxal kinase; LOW QUALITY PROTEIN: pyridoxal kinase

Names: pyridoxal (pyridoxine, vitamin B6) kinase

XP_005639013.2

EC 2.7.1.35

XP_013965253.1

EC 2.7.1.35

XP_038299543.1

EC 2.7.1.35

XP_038299544.1

EC 2.7.1.35

XP_038299545.1

EC 2.7.1.35

XP_038317699.1

EC 2.7.1.35

XP_038373953.1

EC 2.7.1.35

XP_038373954.1

EC 2.7.1.35

XP_038373955.1

EC 2.7.1.35

XP_038437529.1

EC 2.7.1.35

XP_038501919.1

EC 2.7.1.35

XP_038501920.1

EC 2.7.1.35

XP_038501921.1

EC 2.7.1.35

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051835.1 Reference ROS_Cfam_1.0

Range

37225468..37251568

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038443617.1 → XP_038299545.1 pyridoxal kinase isoform X3

UniProtKB/TrEMBL

A0A8I3NV46, A0A8I3P3Y0

Related

ENSCAFP00845025310.1, ENSCAFT00845032379.1

Conserved Domains (1) summary

cl00192
Location:6 → 304

ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
XM_038443615.1 → XP_038299543.1 pyridoxal kinase isoform X1

UniProtKB/TrEMBL

A0A8C0L5R9

Conserved Domains (1) summary

cl00192
Location:7 → 281

ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
XM_038443616.1 → XP_038299544.1 pyridoxal kinase isoform X2

UniProtKB/TrEMBL

A0A8I3NVW3, A0A8I3NWJ0

Related

ENSCAFP00845025557.1, ENSCAFT00845032673.1

Conserved Domains (1) summary

cl00192
Location:1 → 277

ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049291.1 Alternate UMICH_Zoey_3.1

Range

37093275..37121572

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038518027.1 → XP_038373955.1 pyridoxal kinase isoform X3

Conserved Domains (1) summary

cl00192
Location:6 → 304

ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
XM_038518025.1 → XP_038373953.1 pyridoxal kinase isoform X1
XM_038518026.1 → XP_038373954.1 pyridoxal kinase isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049772.1 Alternate UNSW_CanFamBas_1.0

Range

37079116..37107424

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038645993.1 → XP_038501921.1 pyridoxal kinase isoform X3
XM_038645991.1 → XP_038501919.1 pyridoxal kinase isoform X1
XM_038645992.1 → XP_038501920.1 pyridoxal kinase isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049252.1 Alternate UU_Cfam_GSD_1.0

Range

37571216..37599584

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038581601.1 → XP_038437529.1 LOW QUALITY PROTEIN: pyridoxal kinase isoform X3

UniProtKB/TrEMBL

A0A8C0SJ14, A0A8P0PII2

Conserved Domains (1) summary

cl00192
Location:6 → 304

ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006613.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

36836971..36865273

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038461771.1 → XP_038317699.1 pyridoxal kinase isoform X3

UniProtKB/TrEMBL

A0A8C0SJ14, A0A8P0PII2

Conserved Domains (1) summary

cl00192
Location:6 → 304

ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
XM_014109778.2 → XP_013965253.1 pyridoxal kinase isoform X1

UniProtKB/TrEMBL

A0A8C0L5R9

Conserved Domains (1) summary

cl00192
Location:7 → 281

ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
XM_005638956.4 → XP_005639013.2 pyridoxal kinase isoform X2

UniProtKB/TrEMBL

A0A8C0SI18, A0A8P0PDH8, A0A8P0SUQ8

Conserved Domains (1) summary

cl00192
Location:1 → 277

ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...