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    CNOT3 CCR4-NOT transcription complex subunit 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 484312, updated on 5-Mar-2024

    Summary

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    Official Symbol
    CNOT3provided by VGNC
    Official Full Name
    CCR4-NOT transcription complex subunit 3provided by VGNC
    Primary source
    VGNC:VGNC:39414
    See related
    Ensembl:ENSCAFG00845003854
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (103702778..103715996, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (103119211..103132429, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (103815980..103829201, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (103340821..103354027, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (103102254..103115463, complement)

    Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene membrane bound O-acyltransferase domain containing 7 Neighboring gene transmembrane channel like 4 Neighboring gene leukocyte receptor cluster member 1 Neighboring gene pre-mRNA processing factor 31 Neighboring gene uncharacterized LOC106559634 Neighboring gene TCF3 fusion partner

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA poly(A) tail shortening IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of stem cell population maintenance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CCR4-NOT core complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CCR4-NOT transcription complex subunit 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051805.1 Reference ROS_Cfam_1.0

      Range
      103702778..103715996 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038655877.1 → XP_038511805.1  CCR4-NOT transcription complex subunit 3 isoform X3

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 741
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    2. XM_038655874.1 → XP_038511802.1  CCR4-NOT transcription complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8I3MW67, A0A8P0S8I0, A0A8P0TBD5
      Related
      ENSCAFP00845005506.1, ENSCAFT00845006913.1
      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    3. XM_038655873.1 → XP_038511801.1  CCR4-NOT transcription complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8I3MW67, A0A8P0S8I0, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    4. XM_038655876.1 → XP_038511804.1  CCR4-NOT transcription complex subunit 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KWK0, A0A8C0LWB9, A0A8I3MUG6, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 751
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 229
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    5. XM_038655875.1 → XP_038511803.1  CCR4-NOT transcription complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8I3MW67, A0A8P0S8I0, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    6. XM_038655878.1 → XP_038511806.1  CCR4-NOT transcription complex subunit 3 isoform X4

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8P0TBD5
      Related
      ENSCAFP00845005516.1, ENSCAFT00845006925.1
      Conserved Domains (2) summary
      COG5665
      Location:12 → 733
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049261.1 Alternate UMICH_Zoey_3.1

      Range
      103340821..103354027 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038467064.1 → XP_038322992.1  CCR4-NOT transcription complex subunit 3 isoform X3

      Conserved Domains (2) summary
      COG5665
      Location:12 → 741
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    2. XM_038467061.1 → XP_038322989.1  CCR4-NOT transcription complex subunit 3 isoform X1

      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    3. XM_038467060.1 → XP_038322988.1  CCR4-NOT transcription complex subunit 3 isoform X1

      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    4. XM_038467063.1 → XP_038322991.1  CCR4-NOT transcription complex subunit 3 isoform X2

      Conserved Domains (2) summary
      COG5665
      Location:12 → 751
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 229
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    5. XM_038467062.1 → XP_038322990.1  CCR4-NOT transcription complex subunit 3 isoform X1

      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    6. XM_038467065.1 → XP_038322993.1  CCR4-NOT transcription complex subunit 3 isoform X4

      Conserved Domains (2) summary
      COG5665
      Location:12 → 733
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

      Range
      103102254..103115463 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038592102.1 → XP_038448030.1  CCR4-NOT transcription complex subunit 3 isoform X3

      Conserved Domains (2) summary
      COG5665
      Location:12 → 741
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    2. XM_038592099.1 → XP_038448027.1  CCR4-NOT transcription complex subunit 3 isoform X1

      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    3. XM_038592098.1 → XP_038448026.1  CCR4-NOT transcription complex subunit 3 isoform X1

      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    4. XM_038592101.1 → XP_038448029.1  CCR4-NOT transcription complex subunit 3 isoform X2

      Conserved Domains (2) summary
      COG5665
      Location:12 → 751
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 229
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    5. XM_038592100.1 → XP_038448028.1  CCR4-NOT transcription complex subunit 3 isoform X1

      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    6. XM_038592103.1 → XP_038448031.1  CCR4-NOT transcription complex subunit 3 isoform X4

      Conserved Domains (2) summary
      COG5665
      Location:12 → 733
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

      Range
      103815980..103829201 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038527800.1 → XP_038383728.1  CCR4-NOT transcription complex subunit 3 isoform X3

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 741
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    2. XM_038527797.1 → XP_038383725.1  CCR4-NOT transcription complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8I3MW67, A0A8P0S8I0, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    3. XM_038527796.1 → XP_038383724.1  CCR4-NOT transcription complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8I3MW67, A0A8P0S8I0, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    4. XM_038527799.1 → XP_038383727.1  CCR4-NOT transcription complex subunit 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KWK0, A0A8C0LWB9, A0A8I3MUG6, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 751
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 229
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    5. XM_038527798.1 → XP_038383726.1  CCR4-NOT transcription complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8I3MW67, A0A8P0S8I0, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    6. XM_038527801.1 → XP_038383729.1  CCR4-NOT transcription complex subunit 3 isoform X4

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 733
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      103119211..103132429 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022427316.2 → XP_022283024.1  CCR4-NOT transcription complex subunit 3 isoform X3

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 741
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    2. XM_022427298.2 → XP_022283006.1  CCR4-NOT transcription complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8I3MW67, A0A8P0S8I0, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    3. XM_022427294.2 → XP_022283002.1  CCR4-NOT transcription complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8I3MW67, A0A8P0S8I0, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    4. XM_541428.8 → XP_541428.3  CCR4-NOT transcription complex subunit 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KWK0, A0A8C0LWB9, A0A8I3MUG6, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 751
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 229
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    5. XM_038640438.1 → XP_038496366.1  CCR4-NOT transcription complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8I3MW67, A0A8P0S8I0, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 752
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    6. XM_022427317.2 → XP_022283025.1  CCR4-NOT transcription complex subunit 3 isoform X4

      UniProtKB/TrEMBL
      A0A8I3MUG6, A0A8P0TBD5
      Conserved Domains (2) summary
      COG5665
      Location:12 → 733
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 230
      Not3; Not1 N-terminal domain, CCR4-Not complex component
    Nucleotide Protein
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