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    FOXP4 forkhead box P4 [ Canis lupus familiaris (dog) ]

    Gene ID: 481793, updated on 5-Mar-2024

    Summary

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    Official Symbol
    FOXP4provided by VGNC
    Official Full Name
    forkhead box P4provided by VGNC
    Primary source
    VGNC:VGNC:40968
    See related
    Ensembl:ENSCAFG00845015420
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 12
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (10719170..10772709)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (10269034..10322552)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (10427587..10481623)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (10250401..10304021)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (10352401..10387661)

    Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106559582 Neighboring gene uncharacterized LOC111098256 Neighboring gene uncharacterized LOC119874161 Neighboring gene MyoD family inhibitor Neighboring gene transcription factor EB

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    forkhead box protein P4; LOW QUALITY PROTEIN: forkhead box protein P4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051816.1 Reference ROS_Cfam_1.0

      Range
      10719170..10772709
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038683472.1 → XP_038539400.1  forkhead box protein P4 isoform X1

      Conserved Domains (3) summary
      COG5025
      Location:370 → 566
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:473 → 559
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    2. XM_038683476.1 → XP_038539404.1  forkhead box protein P4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QXB3
      Conserved Domains (2) summary
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:461 → 547
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    3. XM_038683474.1 → XP_038539402.1  forkhead box protein P4 isoform X2

      Conserved Domains (3) summary
      COG5025
      Location:369 → 565
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:308 → 375
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:472 → 558
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    4. XM_038683477.1 → XP_038539405.1  forkhead box protein P4 isoform X4

      Conserved Domains (2) summary
      pfam16159
      Location:308 → 375
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:460 → 546
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    5. XM_038683475.1 → XP_038539403.1  forkhead box protein P4 isoform X8

      UniProtKB/TrEMBL
      A0A8C0MKR4, A0A8I3NLA6
      Related
      ENSCAFP00845021666.1, ENSCAFT00845027537.1
      Conserved Domains (3) summary
      COG5025
      Location:365 → 561
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:304 → 371
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:468 → 554
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    6. XM_038683478.1 → XP_038539406.1  forkhead box protein P4 isoform X5

      Related
      ENSCAFP00845021679.1, ENSCAFT00845027554.1
      Conserved Domains (2) summary
      pfam16159
      Location:304 → 371
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:456 → 542
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    7. XM_038683479.1 → XP_038539407.1  forkhead box protein P4 isoform X6

      Conserved Domains (2) summary
      pfam16159
      Location:303 → 370
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:455 → 541
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    8. XM_038683473.1 → XP_038539401.1  forkhead box protein P4 isoform X1

      Conserved Domains (3) summary
      COG5025
      Location:370 → 566
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:473 → 559
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    9. XM_038683480.1 → XP_038539408.1  forkhead box protein P4 isoform X7

      Conserved Domains (3) summary
      COG5025
      Location:315 → 511
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:254 → 321
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:418 → 504
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049272.1 Alternate UMICH_Zoey_3.1

      Range
      10250401..10304021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038491785.1 → XP_038347713.1  forkhead box protein P4 isoform X1

      Conserved Domains (3) summary
      COG5025
      Location:370 → 566
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:473 → 559
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    2. XM_038491789.1 → XP_038347717.1  forkhead box protein P4 isoform X3

      Conserved Domains (2) summary
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:461 → 547
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    3. XM_038491787.1 → XP_038347715.1  forkhead box protein P4 isoform X2

      Conserved Domains (3) summary
      COG5025
      Location:369 → 565
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:308 → 375
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:472 → 558
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    4. XM_038491788.1 → XP_038347716.1  forkhead box protein P4 isoform X8

      Conserved Domains (3) summary
      COG5025
      Location:365 → 561
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:304 → 371
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:468 → 554
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    5. XM_038491790.1 → XP_038347718.1  forkhead box protein P4 isoform X5

      Conserved Domains (2) summary
      pfam16159
      Location:304 → 371
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:456 → 542
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    6. XM_038491791.1 → XP_038347719.1  forkhead box protein P4 isoform X6

      Conserved Domains (2) summary
      pfam16159
      Location:303 → 370
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:455 → 541
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    7. XM_038491786.1 → XP_038347714.1  forkhead box protein P4 isoform X1

      Conserved Domains (3) summary
      COG5025
      Location:370 → 566
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:473 → 559
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    8. XM_038491792.1 → XP_038347720.1  forkhead box protein P4 isoform X7

      Conserved Domains (3) summary
      COG5025
      Location:315 → 511
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:254 → 321
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:418 → 504
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

      Range
      10352401..10387661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038617879.1 → XP_038473807.1  LOW QUALITY PROTEIN: forkhead box protein P4 isoform X8

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

      Range
      10427587..10481623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038554010.1 → XP_038409938.1  forkhead box protein P4 isoform X1

      Conserved Domains (3) summary
      COG5025
      Location:370 → 566
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:473 → 559
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    2. XM_038554015.1 → XP_038409943.1  forkhead box protein P4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QXB3
      Conserved Domains (2) summary
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:461 → 547
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    3. XM_038554012.1 → XP_038409940.1  forkhead box protein P4 isoform X2

      Conserved Domains (3) summary
      COG5025
      Location:369 → 565
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:308 → 375
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:472 → 558
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    4. XM_038554016.1 → XP_038409944.1  forkhead box protein P4 isoform X4

      Conserved Domains (2) summary
      pfam16159
      Location:308 → 375
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:460 → 546
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    5. XM_038554013.1 → XP_038409941.1  forkhead box protein P4 isoform X8

      UniProtKB/TrEMBL
      A0A8C0MKR4, A0A8I3NLA6
      Conserved Domains (3) summary
      COG5025
      Location:365 → 561
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:304 → 371
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:468 → 554
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    6. XM_038554017.1 → XP_038409945.1  forkhead box protein P4 isoform X5

      Conserved Domains (2) summary
      pfam16159
      Location:304 → 371
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:456 → 542
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    7. XM_038554018.1 → XP_038409946.1  forkhead box protein P4 isoform X6

      Conserved Domains (2) summary
      pfam16159
      Location:303 → 370
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:455 → 541
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    8. XM_038554011.1 → XP_038409939.1  forkhead box protein P4 isoform X1

      Conserved Domains (3) summary
      COG5025
      Location:370 → 566
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:473 → 559
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    9. XM_038554019.1 → XP_038409947.1  forkhead box protein P4 isoform X7

      Conserved Domains (3) summary
      COG5025
      Location:315 → 511
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:254 → 321
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:418 → 504
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      10269034..10322552
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005627316.4 → XP_005627373.1  forkhead box protein P4 isoform X1

      Conserved Domains (3) summary
      COG5025
      Location:370 → 566
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:473 → 559
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    2. XM_005627318.4 → XP_005627375.1  forkhead box protein P4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QXB3
      Conserved Domains (2) summary
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:461 → 547
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    3. XM_005627317.4 → XP_005627374.1  forkhead box protein P4 isoform X2

      Conserved Domains (3) summary
      COG5025
      Location:369 → 565
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:308 → 375
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:472 → 558
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    4. XM_538914.8 → XP_538914.4  forkhead box protein P4 isoform X8

      UniProtKB/TrEMBL
      A0A8C0MKR4, A0A8I3NLA6
      Conserved Domains (3) summary
      COG5025
      Location:365 → 561
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:304 → 371
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:468 → 554
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    5. XM_005627319.4 → XP_005627376.1  forkhead box protein P4 isoform X5

      UniProtKB/TrEMBL
      F1PC35
      Conserved Domains (2) summary
      pfam16159
      Location:304 → 371
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:456 → 542
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    6. XM_005627320.4 → XP_005627377.1  forkhead box protein P4 isoform X6

      Conserved Domains (2) summary
      pfam16159
      Location:303 → 370
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:455 → 541
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    7. XM_022426031.1 → XP_022281739.1  forkhead box protein P4 isoform X1

      Conserved Domains (3) summary
      COG5025
      Location:370 → 566
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:309 → 376
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:473 → 559
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins

    8. XM_005627321.4 → XP_005627378.1  forkhead box protein P4 isoform X7

      Conserved Domains (3) summary
      COG5025
      Location:315 → 511
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:254 → 321
      FOXP-CC; FOXP coiled-coil domain
      cd20067
      Location:418 → 504
      FH_FOXP4; Forkhead (FH) domain found in Forkhead box protein P4 (FOXP4) and similar proteins
    Nucleotide Protein
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