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    PCYT1A phosphate cytidylyltransferase 1A, choline [ Canis lupus familiaris (dog) ]

    Gene ID: 478600, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PCYT1Aprovided by VGNC
    Official Full Name
    phosphate cytidylyltransferase 1A, cholineprovided by VGNC
    Primary source
    VGNC:VGNC:44329
    See related
    Ensembl:ENSCAFG00845029954
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PCYT1A in Genome Data Viewer
    Location:
    chromosome: 33
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 33 NC_051837.1 (29596717..29648017, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 33 NC_006615.4 (29387581..29438871, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 33 NC_049254.1 (30060502..30111773, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 33 NC_049293.1 (29386580..29435254, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 33 NC_049774.1 (29437747..29489070, complement)

    Chromosome 33 - NC_051837.1Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 19 Neighboring gene high mobility group protein B3-like Neighboring gene solute carrier family 51 member A Neighboring gene uncharacterized LOC119867351 Neighboring gene dynein light chain Tctex-type 2B Neighboring gene UBX domain protein 7 Neighboring gene uncharacterized LOC119867352

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the intranuclear organelle distribution of CCTalpha is a novel mechanism for the regulation of enzyme activity
      Title: The rate-limiting enzyme in phosphatidylcholine synthesis is associated with nuclear speckles under stress conditions.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables choline-phosphate cytidylyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylcholine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in CDP-choline pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    choline-phosphate cytidylyltransferase A
    Names
    phosphate cytidylyltransferase 1, choline, alpha
    XP_005639655.1
    XP_005639656.1
    XP_038301185.1
    XP_038301186.1
    XP_038301187.1
    XP_038375419.1
    XP_038375420.1
    XP_038375421.1
    XP_038439059.1
    XP_038439060.1
    XP_038439061.1
    XP_038503477.1
    XP_038503478.1
    XP_038503479.1
    XP_535776.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051837.1 Reference ROS_Cfam_1.0

      Range
      29596717..29648017 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038445257.1 → XP_038301185.1  choline-phosphate cytidylyltransferase A

      UniProtKB/TrEMBL
      A0A8C0JPN3, A0A8C0P1R7, A0A8I3Q529, A0A8I3QLF2, A0A8P0TKQ9
      Related
      ENSCAFP00845041685.1, ENSCAFT00845053090.1
      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    2. XM_038445258.1 → XP_038301186.1  choline-phosphate cytidylyltransferase A

      UniProtKB/TrEMBL
      A0A8C0JPN3, A0A8C0P1R7, A0A8I3Q529, A0A8I3QLF2, A0A8P0TKQ9
      Related
      ENSCAFP00845041678.1, ENSCAFT00845053081.1
      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    3. XM_038445259.1 → XP_038301187.1  choline-phosphate cytidylyltransferase A

      UniProtKB/TrEMBL
      A0A8C0JPN3, A0A8C0P1R7, A0A8I3Q529, A0A8I3QLF2, A0A8P0TKQ9
      Related
      ENSCAFP00845041692.1, ENSCAFT00845053098.1
      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049293.1 Alternate UMICH_Zoey_3.1

      Range
      29386580..29435254 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038519492.1 → XP_038375420.1  choline-phosphate cytidylyltransferase A

      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    2. XM_038519493.1 → XP_038375421.1  choline-phosphate cytidylyltransferase A

      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    3. XM_038519491.1 → XP_038375419.1  choline-phosphate cytidylyltransferase A

      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049774.1 Alternate UNSW_CanFamBas_1.0

      Range
      29437747..29489070 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038647549.1 → XP_038503477.1  choline-phosphate cytidylyltransferase A

      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    2. XM_038647550.1 → XP_038503478.1  choline-phosphate cytidylyltransferase A

      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    3. XM_038647551.1 → XP_038503479.1  choline-phosphate cytidylyltransferase A

      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049254.1 Alternate UU_Cfam_GSD_1.0

      Range
      30060502..30111773 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038583131.1 → XP_038439059.1  choline-phosphate cytidylyltransferase A

      UniProtKB/TrEMBL
      A0A8C0JPN3, A0A8C0P1R7, A0A8I3Q529, A0A8I3QLF2, A0A8P0TKQ9
      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    2. XM_038583132.1 → XP_038439060.1  choline-phosphate cytidylyltransferase A

      UniProtKB/TrEMBL
      A0A8C0JPN3, A0A8C0P1R7, A0A8I3Q529, A0A8I3QLF2, A0A8P0TKQ9
      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    3. XM_038583133.1 → XP_038439061.1  choline-phosphate cytidylyltransferase A

      UniProtKB/TrEMBL
      A0A8C0JPN3, A0A8C0P1R7, A0A8I3Q529, A0A8I3QLF2, A0A8P0TKQ9
      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006615.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      29387581..29438871 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_535776.7 → XP_535776.1  choline-phosphate cytidylyltransferase A

      See identical proteins and their annotated locations for XP_535776.1

      UniProtKB/TrEMBL
      A0A8C0JPN3, A0A8C0P1R7, A0A8I3Q529, A0A8I3QLF2, A0A8P0TKQ9
      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    2. XM_005639598.4 → XP_005639655.1  choline-phosphate cytidylyltransferase A

      See identical proteins and their annotated locations for XP_005639655.1

      UniProtKB/TrEMBL
      A0A8C0JPN3, A0A8C0P1R7, A0A8I3Q529, A0A8I3QLF2, A0A8P0TKQ9
      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase

    3. XM_005639599.4 → XP_005639656.1  choline-phosphate cytidylyltransferase A

      See identical proteins and their annotated locations for XP_005639656.1

      UniProtKB/TrEMBL
      A0A8C0JPN3, A0A8C0P1R7, A0A8I3Q529, A0A8I3QLF2, A0A8P0TKQ9
      Conserved Domains (1) summary
      cd02174
      Location:75 → 224
      CCT; CTP:phosphocholine cytidylyltransferase
    Nucleotide Protein
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