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    KLC4 kinesin light chain 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 474909, updated on 5-Mar-2024

    Summary

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    Official Symbol
    KLC4provided by VGNC
    Official Full Name
    kinesin light chain 4provided by VGNC
    Primary source
    VGNC:VGNC:42429
    See related
    Ensembl:ENSCAFG00845007804
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See KLC4 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (12060004..12073081)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (11605669..11618744)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (11766786..11779863)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (11588642..11601719)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (11672710..11685998)

    Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene cullin 7 Neighboring gene mitochondrial ribosomal protein L2 Neighboring gene protein tyrosine kinase 7 (inactive) Neighboring gene oligosaccharyltransferase complex subunit OSTC Neighboring gene uncharacterized LOC111098263 Neighboring gene serum response factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kinesin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axo-dendritic transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of kinesin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kinesin light chain 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051816.1 Reference ROS_Cfam_1.0

      Range
      12060004..12073081
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038683580.1 → XP_038539508.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    2. XM_038683578.1 → XP_038539506.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Related
      ENSCAFP00845010962.1, ENSCAFT00845014143.1
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    3. XM_038683583.1 → XP_038539511.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    4. XM_038683579.1 → XP_038539507.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    5. XM_038683582.1 → XP_038539510.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Related
      ENSCAFP00845010784.1, ENSCAFT00845013914.1
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    6. XM_038683581.1 → XP_038539509.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Related
      ENSCAFP00845010916.1, ENSCAFT00845014086.1
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    7. XM_038683584.1 → XP_038539512.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049272.1 Alternate UMICH_Zoey_3.1

      Range
      11588642..11601719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038491862.1 → XP_038347790.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    2. XM_038491860.1 → XP_038347788.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    3. XM_038491865.1 → XP_038347793.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    4. XM_038491861.1 → XP_038347789.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    5. XM_038491864.1 → XP_038347792.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    6. XM_038491863.1 → XP_038347791.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    7. XM_038491866.1 → XP_038347794.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

      Range
      11672710..11685998
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038617979.1 → XP_038473907.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    2. XM_038617977.1 → XP_038473905.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    3. XM_038617983.1 → XP_038473911.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    4. XM_038617978.1 → XP_038473906.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    5. XM_038617981.1 → XP_038473909.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    6. XM_038617980.1 → XP_038473908.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    7. XM_038617984.1 → XP_038473912.1  kinesin light chain 4

      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

      Range
      11766786..11779863
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038554119.1 → XP_038410047.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    2. XM_038554117.1 → XP_038410045.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    3. XM_038554122.1 → XP_038410050.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    4. XM_038554118.1 → XP_038410046.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    5. XM_038554121.1 → XP_038410049.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    6. XM_038554120.1 → XP_038410048.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    7. XM_038554123.1 → XP_038410051.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      11605669..11618744
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014118455.3 → XP_013973930.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    2. XM_005627377.4 → XP_005627434.1  kinesin light chain 4

      See identical proteins and their annotated locations for XP_005627434.1

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    3. XM_014118457.3 → XP_013973932.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    4. XM_014118454.3 → XP_013973929.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    5. XM_005627378.4 → XP_005627435.1  kinesin light chain 4

      See identical proteins and their annotated locations for XP_005627435.1

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    6. XM_038673764.1 → XP_038529692.1  kinesin light chain 4

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat

    7. XM_005627372.4 → XP_005627429.1  kinesin light chain 4

      See identical proteins and their annotated locations for XP_005627429.1

      UniProtKB/TrEMBL
      A0A8C0KFA2, A0A8C0N7J6, A0A8C0NA31, A0A8I3N7B5, A0A8I3NIZ3
      Conserved Domains (3) summary
      TIGR02168
      Location:33 → 148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      sd00006
      Location:292 → 320
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:291 → 365
      TPR_12; Tetratricopeptide repeat
    Nucleotide Protein
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