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    CDX2 caudal type homeobox 2 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 467350, updated on 29-Mar-2024

    Summary

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    Official Symbol
    CDX2provided by VGNC
    Official Full Name
    caudal type homeobox 2provided by VGNC
    Primary source
    VGNC:VGNC:13071
    Locus tag
    CK820_G0032566
    See related
    Ensembl:ENSPTRG00000043330
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 13
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 14 NC_072412.2 (27122661..27131142, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 13 NC_072411.1 (21895438..21903835, complement)

    Chromosome 14 - NC_072412.2Genomic Context describing neighboring genes Neighboring gene ATP synthase subunit epsilon-like protein, mitochondrial Neighboring gene uncharacterized LOC134808116 Neighboring gene ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase Neighboring gene fms related receptor tyrosine kinase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anterior/posterior axis specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in embryo development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeobox protein CDX-2
    Names
    caudal type homeo box transcription factor 2
    caudal type homeobox transcription factor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072412.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      27122661..27131142 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016925110.4 → XP_016780599.1  homeobox protein CDX-2 isoform X1

      UniProtKB/TrEMBL
      A0A2I3RZR9, A0A2J8L5A2, A0A6D2XAZ6
      Related
      ENSPTRP00000070197.1
      Conserved Domains (2) summary
      pfam00046
      Location:190 → 242
      Homeobox; Homeobox domain
      pfam04731
      Location:13 → 171
      Caudal_act; Caudal like protein activation region

    2. XM_024348490.3 → XP_024204258.1  homeobox protein CDX-2 isoform X2

      Conserved Domains (2) summary
      pfam04731
      Location:13 → 171
      Caudal_act; Caudal like protein activation region
      cl00084
      Location:190 → 228
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    Nucleotide Protein
    Heading Accession and Version

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