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    ASB3 ankyrin repeat and SOCS box containing 3 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 459227, updated on 10-Apr-2024

    Summary

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    Official Symbol
    ASB3provided by VGNC
    Official Full Name
    ankyrin repeat and SOCS box containing 3provided by VGNC
    Primary source
    VGNC:VGNC:10522
    Locus tag
    CK820_G0015057
    See related
    Ensembl:ENSPTRG00000011916
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2A
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 12 NC_072410.2 (68861182..68981713)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2A NC_072399.1 (53871526..53991025, complement)

    Chromosome 12 - NC_072410.2Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene G protein-coupled receptor 75 Neighboring gene endoplasmic reticulum lectin 1 Neighboring gene ChaC glutathione specific gamma-glutamylcyclotransferase 2 Neighboring gene uncharacterized LOC104004971 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to ciliary inversin compartment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in ciliary inversin compartment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ankyrin repeat and SOCS box protein 3
    Names
    GPR75-ASB3
    ankyrin repeat and SOCS box-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205040.3 → NP_001191969.1  ankyrin repeat and SOCS box protein 3

      See identical proteins and their annotated locations for NP_001191969.1

      Status: PROVISIONAL

      Source sequence(s)
      JAQQLN020000012
      UniProtKB/TrEMBL
      H2QHW7
      Related
      ENSPTRP00000020462.3, ENSPTRT00000022176.4
      Conserved Domains (3) summary
      cd00204
      Location:146 → 267
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd03722
      Location:457 → 507
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:146 → 176
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072410.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      68861182..68981713
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063788802.1 → XP_063644872.1  ankyrin repeat and SOCS box protein 3 isoform X7

    2. XM_063788799.1 → XP_063644869.1  ankyrin repeat and SOCS box protein 3 isoform X2

    3. XM_024354089.3 → XP_024209857.1  ankyrin repeat and SOCS box protein 3 isoform X4

      UniProtKB/TrEMBL
      H2QHW7
      Conserved Domains (3) summary
      cd00204
      Location:146 → 267
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd03722
      Location:457 → 507
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:146 → 176
      ANK; ANK repeat [structural motif]

    4. XM_063788800.1 → XP_063644870.1  ankyrin repeat and SOCS box protein 3 isoform X3

    5. XM_054677172.2 → XP_054533147.1  ankyrin repeat and SOCS box protein 3 isoform X9

      UniProtKB/TrEMBL
      G2HJ21

    6. XM_063788804.1 → XP_063644874.1  ankyrin repeat and SOCS box protein 3 isoform X9

      UniProtKB/TrEMBL
      G2HJ21

    7. XM_054677180.2 → XP_054533155.1  ankyrin repeat and SOCS box protein 3 isoform X10

    8. XM_054677167.2 → XP_054533142.1  ankyrin repeat and SOCS box protein 3 isoform X6

    9. XM_063788803.1 → XP_063644873.1  ankyrin repeat and SOCS box protein 3 isoform X8

    10. XM_054677158.2 → XP_054533133.1  ankyrin repeat and SOCS box protein 3 isoform X4

      UniProtKB/TrEMBL
      H2QHW7

    11. XM_063788801.1 → XP_063644871.1  ankyrin repeat and SOCS box protein 3 isoform X4

      UniProtKB/TrEMBL
      H2QHW7

    12. XM_009442327.5 → XP_009440602.2  ankyrin repeat and SOCS box protein 3 isoform X1

    13. XM_054677160.2 → XP_054533135.1  ankyrin repeat and SOCS box protein 3 isoform X5

    14. XM_054677174.2 → XP_054533149.1  ankyrin repeat and SOCS box protein 3 isoform X9

      UniProtKB/TrEMBL
      G2HJ21
    Nucleotide Protein
    Heading Accession and Version

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