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    MR1 major histocompatibility complex, class I-related [ Pan troglodytes (chimpanzee) ]

    Gene ID: 457562, updated on 29-Mar-2024

    Summary

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    Gene symbol
    MR1
    Gene description
    major histocompatibility complex, class I-related
    Locus tag
    CK820_G0013608
    See related
    Ensembl:ENSPTRG00000001746
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (68079391..68112179, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (163248242..163270335)

    Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129143241 Neighboring gene immediate early response 5 Neighboring gene syntaxin 6 Neighboring gene putative uncharacterized protein encoded by LINC00269 Neighboring gene major histocompatibility complex class I-related gene protein-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the MHC class I-related MR1 locus in nonhuman primates. Parra-Cuadrado JF, et al. Immunogenetics, 2001 Oct. PMID 11797097

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in antigen processing and presentation of endogenous peptide antigen via MHC class Ib IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell mediated cytotoxicity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    major histocompatibility complex class I-related gene protein
    Names
    MHC class I-related gene protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001071790.1 → NP_001065258.1  major histocompatibility complex class I-related gene protein precursor

      See identical proteins and their annotated locations for NP_001065258.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ275985
      UniProtKB/TrEMBL
      A0A2J8N6P1, A0A6D2WFA9, H2R2K7
      Related
      ENSPTRP00000044099.5, ENSPTRT00000045675.6
      Conserved Domains (1) summary
      cl08246
      Location:25 → 198
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      68079391..68112179 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063787926.1 → XP_063643996.1  major histocompatibility complex class I-related gene protein isoform X1

    2. XM_063788006.1 → XP_063644076.1  major histocompatibility complex class I-related gene protein isoform X2

    3. XM_063787980.1 → XP_063644050.1  major histocompatibility complex class I-related gene protein isoform X2

    4. XM_016963020.4 → XP_016818509.1  major histocompatibility complex class I-related gene protein isoform X1

      UniProtKB/TrEMBL
      A0A2I3TMI0, A0A2J8N6N6, A0A6D2Y184
      Related
      ENSPTRP00000090456.1
      Conserved Domains (2) summary
      cd07698
      Location:198 → 290
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      cl08246
      Location:21 → 194
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    5. XM_063788103.1 → XP_063644173.1  major histocompatibility complex class I-related gene protein isoform X3

    6. XM_063788168.1 → XP_063644238.1  major histocompatibility complex class I-related gene protein isoform X4

    7. XM_054658132.2 → XP_054514107.1  major histocompatibility complex class I-related gene protein isoform X2

    8. XM_063788145.1 → XP_063644215.1  major histocompatibility complex class I-related gene protein isoform X4

    9. XM_063788031.1 → XP_063644101.1  major histocompatibility complex class I-related gene protein isoform X2

    10. XM_054658157.2 → XP_054514132.1  major histocompatibility complex class I-related gene protein isoform X2

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9BCU3.1 GenPept UniProtKB/Swiss-Prot:Q9BCU3

    Gene LinkOut

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