PFKP phosphofructokinase, platelet [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PFKPprovided by VGNC
Official Full Name: phosphofructokinase, plateletprovided by VGNC
Primary source: VGNC:VGNC:5624
Locus tag: CK820_G0036153
See related: Ensembl:ENSPTRG00000002243
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 10

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	8	NC_072406.2 (15888524..15960270)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	10	NC_072408.1 (6223763..6295526)

Chromosome 8 - NC_072406.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

G62086 (e-PCR)
- UniSTS:139092

GDB:193844 (e-PCR)
- UniSTS:155760

RH15729 (e-PCR)
- UniSTS:37765

SHGC-146866 (e-PCR)
- UniSTS:172701

RH103121 (e-PCR)
- UniSTS:97455

D10S1218 (e-PCR), detects polymorphism
- UniSTS:58584

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 6-phosphofructokinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables AMP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables fructose-6-phosphate binding	IEA Inferred from Electronic Annotation more info	PubMed
enables identical protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables monosaccharide binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in canonical glycolysis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in fructose 1,6-bisphosphate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in fructose 6-phosphate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of 6-phosphofructokinase complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: 6-phosphofructokinase type C; ATP-dependent 6-phosphofructokinase, platelet type

XP_016818043.2

EC 2.7.1.11

XP_016818044.1

EC 2.7.1.11

XP_054516628.2

EC 2.7.1.11

XP_054516631.1

EC 2.7.1.11

XP_063637370.1

EC 2.7.1.11

XP_063637371.1

EC 2.7.1.11

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

15888524..15960270

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016962555.4 → XP_016818044.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X5

UniProtKB/TrEMBL

A0A2J8KTY7, A0A8I3B2U8, H2Q1J5, K6ZKG6, K7C3C5

Related

ENSPTRP00000003790.6

Conserved Domains (1) summary

cd00764
Location:22 → 783

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
XM_016962554.3 → XP_016818043.2 ATP-dependent 6-phosphofructokinase, platelet type isoform X2
XM_054660656.2 → XP_054516631.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X6
XM_063781300.1 → XP_063637370.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X3
XM_063781301.1 → XP_063637371.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X4
XM_054660653.2 → XP_054516628.2 ATP-dependent 6-phosphofructokinase, platelet type isoform X1