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    erlin2.S ER lipid raft associated 2 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 444675, updated on 11-Apr-2024

    Summary

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    Official Symbol
    erlin2.S
    Official Full Name
    ER lipid raft associated 2 S homeolog
    Primary source
    Xenbase:XB-GENE-6254593
    Locus tag
    XELAEV_18020387mg
    See related
    EnsemblRapid:ENSXLAG00005016144
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    spfh1; spfh2; erlin1; erlin2; spfh2-B; erlin2-a; erlin2-b; Erlin-2-B
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    Genomic context

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    See erlin2.S in Genome Data Viewer
    Location:
    chromosome: 3S
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (34894398..34912708)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (33704130..33722441)

    Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene unc-5 netrin receptor D S homeolog Neighboring gene zinc finger protein 703 S homeolog Neighboring gene pyridoxal phosphate homeostasis protein-like Neighboring gene adhesion G protein-coupled receptor A2 S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC84282

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables cholesterol binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within SREBP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cholesterol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    erlin-2-B
    Names
    ER lipid raft associated 1
    Endoplasmic reticulum lipid raft-associated protein 2-B
    SPFH domain-containing protein 2-B
    Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2-B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001092777.1 → NP_001086246.1  erlin-2-B

      See identical proteins and their annotated locations for NP_001086246.1

      Status: PROVISIONAL

      Source sequence(s)
      BC074372
      UniProtKB/Swiss-Prot
      Q6DKC0
      UniProtKB/TrEMBL
      A0A974D7P0
      Related
      ENSXLAP00005047525.1, ENSXLAT00005048635.1
      Conserved Domains (2) summary
      smart00244
      Location:21 → 187
      PHB; prohibitin homologues
      cd03406
      Location:16 → 308
      SPFH_like_u3; Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      34894398..34912708
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6DKC0.1 GenPept UniProtKB/Swiss-Prot:Q6DKC0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.