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    AQP4 aquaporin 4 [ Ovis aries (sheep) ]

    Gene ID: 443268, updated on 5-Mar-2024

    Summary

    Gene symbol
    AQP4
    Gene description
    aquaporin 4
    See related
    EnsemblRapid:ENSOARG00020025374
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 23
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 23 NC_056076.1 (30388118..30402743)

    Chromosome 23 - NC_056076.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene carbohydrate sulfotransferase 9 Neighboring gene uncharacterized LOC105604443 Neighboring gene potassium channel tetramerization domain containing 1 Neighboring gene transfer RNA cysteine (anticodon ACA)

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_056076.1 Chromosome 23 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables water channel activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in basolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    aquaporin-4
    Names
    mercurial insensitive water channel
    water channel

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009279.1NP_001009279.1  aquaporin-4

      See identical proteins and their annotated locations for NP_001009279.1

      Status: PROVISIONAL

      Source sequence(s)
      AY304480
      UniProtKB/TrEMBL
      A0A6P3CWH7, Q866S4
      Related
      ENSOARP00020032994.2, ENSOART00020039816.2
      Conserved Domains (1) summary
      pfam00230
      Location:31248
      MIP; Major intrinsic protein

    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056076.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      30388118..30402743
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012103244.5XP_011958634.1  aquaporin-4 isoform X1

      See identical proteins and their annotated locations for XP_011958634.1

      UniProtKB/TrEMBL
      A0A6P3TFZ5, Q6XVT6
      Related
      ENSOARP00020051990.1, ENSOART00020080395.1
      Conserved Domains (1) summary
      pfam00230
      Location:9226
      MIP; Major intrinsic protein
    2. XM_012103243.4XP_011958633.1  aquaporin-4 isoform X1

      See identical proteins and their annotated locations for XP_011958633.1

      UniProtKB/TrEMBL
      A0A6P3TFZ5, Q6XVT6
      Related
      ENSOARP00020033010.2, ENSOART00020039833.2
      Conserved Domains (1) summary
      pfam00230
      Location:9226
      MIP; Major intrinsic protein