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    HR HR lysine demethylase and nuclear receptor corepressor [ Ovis aries (sheep) ]

    Gene ID: 443241, updated on 5-Mar-2024

    Summary

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    Gene symbol
    HR
    Gene description
    HR lysine demethylase and nuclear receptor corepressor
    See related
    EnsemblRapid:ENSOARG00020022176
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (43475486..43494705)

    Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat LGI family member 3 Neighboring gene receptor accessory protein 4 Neighboring gene HR upstream open reading frame Neighboring gene nudix hydrolase 18 Neighboring gene FHF complex subunit HOOK interacting protein 2B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The hairless (hr) gene is involved in the congenital hypotrichosis of Valle del Belice sheep. Finocchiaro R, et al. Genet Sel Evol, 2003. PMID 12927087, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone H3K9 demethylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of histone deacetylase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lysine-specific demethylase hairless
    Names
    hair growth associated
    hairless homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      43475486..43494705
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004004200.6 → XP_004004249.2  lysine-specific demethylase hairless isoform X4

      UniProtKB/TrEMBL
      W5PLC3

    2. XM_042243154.2 → XP_042099088.1  lysine-specific demethylase hairless isoform X1

      UniProtKB/TrEMBL
      W5PLC3
      Conserved Domains (1) summary
      cl28890
      Location:593 → 620
      FYVE_like_SF; FYVE domain like superfamily

    3. XM_027964354.3 → XP_027820155.1  lysine-specific demethylase hairless isoform X3

      UniProtKB/TrEMBL
      W5PLC3
      Related
      ENSOARP00020028790.2, ENSOART00020034863.2

    4. XM_042243156.2 → XP_042099090.1  lysine-specific demethylase hairless isoform X2

      UniProtKB/TrEMBL
      W5PLC3
      Conserved Domains (1) summary
      cl28890
      Location:592 → 619
      FYVE_like_SF; FYVE domain like superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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