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    MYOG myogenin [ Ovis aries (sheep) ]

    Gene ID: 443158, updated on 5-Mar-2024

    Summary

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    Gene symbol
    MYOG
    Gene description
    myogenin
    See related
    EnsemblRapid:ENSOARG00020003647
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 12 NC_056065.1 (591923..593948, complement)

    Chromosome 12 - NC_056065.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 183A Neighboring gene PTPRF interacting protein alpha 4 Neighboring gene annexin A2-like Neighboring gene uncharacterized LOC121820747 Neighboring gene adenosine A1 receptor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056065.1 Chromosome 12 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and expression of MyoG gene from Hu sheep and identification of its myogenic specificity. Zhang Z, et al. Mol Biol Rep, 2014 Feb. PMID 24385300
    2. Developmental changes in IGF-I and MyoG gene expression and their association with meat traits in sheep. Sun W, et al. Genet Mol Res, 2014 Apr 14. PMID 24782091
    3. Correlation between sheep YAP1 temporal and spatial expression trends and MSTN and MyoG gene expression. Lv XY, et al. Genet Mol Res, 2015 Apr 13. PMID 25966090

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that Yes-associated protein 1 (YAP1) expression was significantly or and positively correlated with (MSTN) and myogenin (MyoG) at 2 days old, 2 and 6 months old.
      Title: Correlation between sheep YAP1 temporal and spatial expression trends and MSTN and MyoG gene expression.
    2. We conclude that the expressions of IGF-I and MyoG genes are significantly and positively correlated with early muscle traits of Hu sheep
      Title: Developmental changes in IGF-I and MyoG gene expression and their association with meat traits in sheep.
    3. The subcellular localization and myogenic activity of MyoG were exactly detected on the basis of multiple biological analyses, which expanded our understanding of the biological function of MyoG.
      Title: Cloning and expression of MyoG gene from Hu sheep and identification of its myogenic specificity.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in muscle organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of myoblast differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myogenin
    Names
    myogenin (myogenic factor 4)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001174109.1 → NP_001167580.1  myogenin

      See identical proteins and their annotated locations for NP_001167580.1

      Status: PROVISIONAL

      Source sequence(s)
      GU550517
      UniProtKB/TrEMBL
      A0A6P3CXP7, A0A836CWX1, D3YKV7
      Related
      ENSOARP00020004578.2, ENSOART00020005560.2
      Conserved Domains (2) summary
      smart00520
      Location:1 → 86
      BASIC; Basic domain in HLH proteins of MYOD family
      pfam00010
      Location:82 → 133
      HLH; Helix-loop-helix DNA-binding domain

    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056065.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      591923..593948 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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