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    GPR50 G protein-coupled receptor 50 [ Ovis aries (sheep) ]

    Gene ID: 443023, updated on 5-Mar-2024

    Summary

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    Gene symbol
    GPR50
    Gene description
    G protein-coupled receptor 50
    See related
    EnsemblRapid:ENSOARG00020007042
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) X NC_056080.1 (84491263..84495824, complement)

    Chromosome X - NC_056080.1Genomic Context describing neighboring genes Neighboring gene PAS domain containing repressor 1 Neighboring gene vacuolar ATPase assembly factor VMA21 Neighboring gene high mobility group box 3 Neighboring gene CD99 molecule like 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056080.1 Chromosome X Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ovine melatonin-related receptor: cloning and preliminary distribution and binding studies. Drew JE, et al. J Neuroendocrinol, 1998 Sep. PMID 9744482
    2. Neuroanatomical distribution of the orphan GPR50 receptor in adult sheep and rodent brains. Batailler M, et al. J Neuroendocrinol, 2012 May. PMID 22512326
    3. Cloning of a melatonin-related receptor from human pituitary. Reppert SM, et al. FEBS Lett, 1996 May 20. PMID 8647286

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. An enlarged distribution of GPR50 protein in the brain.
      Title: Neuroanatomical distribution of the orphan GPR50 receptor in adult sheep and rodent brains.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables melatonin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    melatonin-related receptor
    Names
    H9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009726.1 → NP_001009726.1  melatonin-related receptor

      See identical proteins and their annotated locations for NP_001009726.1

      Status: PROVISIONAL

      Source sequence(s)
      AF047829
      UniProtKB/Swiss-Prot
      O46624, Q28558
      UniProtKB/TrEMBL
      W5PG27
      Related
      ENSOARP00020008867.1, ENSOART00020010777.2
      Conserved Domains (2) summary
      pfam00001
      Location:45 → 294
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:39 → 181
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056080.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      84491263..84495824 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28558.2 GenPept UniProtKB/Swiss-Prot:Q28558

    Gene LinkOut

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