IFNA5 interferon, alpha 5 [Canis lupus familiaris (dog)] - Gene

Summary

Gene symbol: IFNA5
Gene description: interferon, alpha 5
See related: Ensembl:ENSCAFG00845016367
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: IFN-alpha; CAIFN-ALPHA 5
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Genomic context

Location:: chromosome: 11

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	11	NC_051815.1 (41671573..41672136, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	11	NC_006593.4 (39392080..39392643, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	11	NC_049232.1 (40787666..40788229, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	11	NC_049271.1 (40363568..40364130, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	11	NC_049752.1 (40152526..40153089, complement)

Chromosome 11 - NC_051815.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed
enables type I interferon receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in B cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in B cell proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in T cell activation involved in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cytokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in defense response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in humoral immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in natural killer cell activation involved in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of peptidyl-serine phosphorylation of STAT protein	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to exogenous dsRNA	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interferon alpha-3

Names: CaIFN-alpha 6; CaIFN-alpha 8; IFN-alpha-3; Interferon alpha-3; interferon-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006647.1 → NP_001006648.1 interferon alpha-3 precursor

See identical proteins and their annotated locations for NP_001006648.1

Status: PROVISIONAL

Source sequence(s)

AB125934

UniProtKB/TrEMBL

A0A8C0M4T8, F8SU61, Q75UL7

Related

ENSCAFP00845022846.1, ENSCAFT00845029045.1

Conserved Domains (1) summary

cd00095
Location:26 → 176

IFab; Interferon alpha, beta. Includes also interferon omega and tau. Different from interferon gamma family. Type I interferons(alpha, beta) belong to the larger helical cytokine superfamily, which includes growth hormones, interleukins, several ...