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    ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 [ Gallus gallus (chicken) ]

    Gene ID: 427428, updated on 3-Apr-2024

    Summary

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    Symbol
    ADAMTS12provided by CGNC
    Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 12provided by CGNC
    Primary source
    CGNC:2393
    See related
    Ensembl:ENSGALG00010013174
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Z
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (10692168..10863128, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (10692168..10863128, complement)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene natriuretic peptide receptor 3 Neighboring gene threonyl-tRNA synthetase Neighboring gene uncharacterized LOC121108607 Neighboring gene uncharacterized LOC124417551 Neighboring gene relaxin/insulin like family peptide receptor 3 Neighboring gene solute carrier family 45 member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      10692168..10863128 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003642975.6 → XP_003643023.3  A disintegrin and metalloproteinase with thrombospondin motifs 12 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YIS9, A0A8V0YIT3
      Related
      ENSGALP00010018467.1, ENSGALT00010031599.1
      Conserved Domains (4) summary
      smart00209
      Location:551 → 602
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:252 → 459
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam05986
      Location:709 → 818
      ADAM_spacer1; ADAM-TS Spacer 1
      cl15456
      Location:521 → 682
      ADAM_CR; ADAM cysteine-rich

    2. XM_015277506.4 → XP_015132992.2  A disintegrin and metalloproteinase with thrombospondin motifs 12 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YQQ9
      Related
      ENSGALP00010018506.1, ENSGALT00010031642.1
      Conserved Domains (4) summary
      smart00209
      Location:551 → 602
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:252 → 459
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam05986
      Location:709 → 818
      ADAM_spacer1; ADAM-TS Spacer 1
      cl15456
      Location:521 → 682
      ADAM_CR; ADAM cysteine-rich

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      10692168..10863128 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046936341.1 → XP_046792297.1  A disintegrin and metalloproteinase with thrombospondin motifs 12 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YIS9

    2. XM_046936342.1 → XP_046792298.1  A disintegrin and metalloproteinase with thrombospondin motifs 12 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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