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    LETM1 leucine zipper and EF-hand containing transmembrane protein 1 [ Gallus gallus (chicken) ]

    Gene ID: 422898, updated on 3-Apr-2024

    Summary

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    Symbol
    LETM1provided by CGNC
    Full Name
    leucine zipper and EF-hand containing transmembrane protein 1provided by CGNC
    Primary source
    CGNC:11714
    See related
    Ensembl:ENSGALG00010016924
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    KHE
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (82799556..82853645)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (82777900..82831966)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene small Cajal body-specific RNA 23 Neighboring gene down-regulated in colon cancer 1 Neighboring gene Wolf-Hirschhorn syndrome candidate 1 Neighboring gene ADP/ATP translocase 4-like Neighboring gene fibroblast growth factor receptor 3 Neighboring gene uncharacterized LOC101749105

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular monoatomic cation homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial proton/calcium exchanger protein
    Names
    LETM1 and EF-hand domain-containing protein 1, mitochondrial
    electroneutral mitochondrial K(+)/H(+)exchanger
    leucine zipper-EF-hand-containing transmembrane protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006461.4 → NP_001006461.2  mitochondrial proton/calcium exchanger protein

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000074
      UniProtKB/Swiss-Prot
      Q5ZK33
      Related
      ENSGALP00010023834.1, ENSGALT00010040870.1
      Conserved Domains (3) summary
      pfam07766
      Location:155 → 410
      LETM1; LETM1-like protein
      cl00591
      Location:589 → 693
      FlaG; FlaG protein
      cl17037
      Location:457 → 561
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      82799556..82853645
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046940227.1 → XP_046796183.1  mitochondrial proton/calcium exchanger protein isoform X2

      Related
      ENSGALP00010023837.1, ENSGALT00010040873.1

    2. XM_046940226.1 → XP_046796182.1  mitochondrial proton/calcium exchanger protein isoform X2

    3. XM_015285900.4 → XP_015141386.1  mitochondrial proton/calcium exchanger protein isoform X1

      UniProtKB/Swiss-Prot
      Q5ZK33
      Conserved Domains (3) summary
      COG5126
      Location:600 → 715
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      pfam07766
      Location:155 → 410
      LETM1; LETM1-like protein
      cl17037
      Location:457 → 561
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      82777900..82831966
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046916388.1 → XP_046772344.1  mitochondrial proton/calcium exchanger protein isoform X2

    2. XM_046916387.1 → XP_046772343.1  mitochondrial proton/calcium exchanger protein isoform X2

    3. XM_046916386.1 → XP_046772342.1  mitochondrial proton/calcium exchanger protein isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5ZK33.1 GenPept UniProtKB/Swiss-Prot:Q5ZK33

    Gene LinkOut

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