WDR1 WD repeat domain 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: WDR1provided by CGNC
Full Name: WD repeat domain 1provided by CGNC
Primary source: CGNC:11108
See related: Ensembl:ENSGALG00010009542
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	4	NC_052535.1 (77832057..77851901)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	4	NC_052576.1 (77810794..77830636)

Chromosome 4 - NC_052535.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Elevated WDR1 expression in the avian vestibule may have a role in the hair cell regenerating ability as in the avian cochlea
Title: WDR1 expression in the normal and noise-damaged chick vestibule.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin filament binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin filament depolymerization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in locomotion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of actin filament depolymerization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sarcomere organization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cortical actin cytoskeleton	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: WD repeat-containing protein 1

Names: AIP1; actin-interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001004402.2 → NP_001004402.2 WD repeat-containing protein 1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000074

UniProtKB/Swiss-Prot

O93277

Related

ENSGALP00010013153.1, ENSGALT00010022757.1

Conserved Domains (3) summary

COG2319
Location:233 → 607

WD40; WD40 repeat [General function prediction only]

cd00200
Location:56 → 391

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:64 → 102

7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

77832057..77851901

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040699043.2 → XP_040554977.1 WD repeat-containing protein 1 isoform X1

UniProtKB/Swiss-Prot

O93277

Conserved Domains (3) summary

cd00200
Location:91 → 468

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:59 → 96

7WD40; WD40 repeat [structural motif]

cl29593
Location:433 → 514

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...