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    CD34 CD34 molecule [ Canis lupus familiaris (dog) ]

    Gene ID: 415130, updated on 5-Mar-2024

    Summary

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    Official Symbol
    CD34provided by VGNC
    Official Full Name
    CD34 moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:38950
    See related
    Ensembl:ENSCAFG00845002498
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 7
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (6422992..6447293, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (6297083..6321394, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (6499295..6523438, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (6355774..6380048, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (6458250..6482488, complement)

    Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119872489 Neighboring gene uncharacterized LOC119872657 Neighboring gene uncharacterized LOC102151524 Neighboring gene uncharacterized LOC111096860

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CD34 positive cells seeded on small caliber man-made vascular grafts exhibit increased antithrombogenic property compared with unfractioned mononuclear cells. Wang F, et al. J Cardiovasc Surg (Torino), 2010 Dec. PMID 21124286
    2. Canine gastrointestinal stromal tumors: immunohistochemical expression of CD34 and examination of prognostic indicators including proliferation markers Ki67 and AgNOR. Gillespie V, et al. Vet Pathol, 2011 Jan. PMID 20826846
    3. Canine CD34: cloning of the cDNA and evaluation of an antiserum to recombinant protein. McSweeney PA, et al. Blood, 1996 Sep 15. PMID 8822918

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The gross, histologic, and immunohistochemical features of gastrointestinal stromal tumors, especially the expression of CD34 and Ki67, are reported.
      Title: Canine gastrointestinal stromal tumors: immunohistochemical expression of CD34 and examination of prognostic indicators including proliferation markers Ki67 and AgNOR.
    2. CD34+ cells exerted better antithrombogenic property than unfractioned mononuclear cells after seeding onto the small caliber vessel grafts.
      Title: CD34 positive cells seeded on small caliber man-made vascular grafts exhibit increased antithrombogenic property compared with unfractioned mononuclear cells.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hematopoietic progenitor cell antigen CD34
    Names
    CD34 antigen
    hematopoietic progenitor cell marker CD34

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003341.1 → NP_001003341.1  hematopoietic progenitor cell antigen CD34 precursor

      See identical proteins and their annotated locations for NP_001003341.1

      Status: PROVISIONAL

      Source sequence(s)
      U49457
      UniProtKB/Swiss-Prot
      Q28270
      UniProtKB/TrEMBL
      A0A8C0R049, A0A8C0ST54, A0A8I3MPV5
      Related
      ENSCAFP00845003563.1, ENSCAFT00845004455.1
      Conserved Domains (1) summary
      pfam06365
      Location:196 → 388
      CD34_antigen; CD34/Podocalyxin family

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051811.1 Reference ROS_Cfam_1.0

      Range
      6422992..6447293 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038670500.1 → XP_038526428.1  hematopoietic progenitor cell antigen CD34 isoform X1

      UniProtKB/TrEMBL
      A0A8C0R049, A0A8C0ST54, A0A8I3MPV5
      Conserved Domains (1) summary
      pfam06365
      Location:196 → 332
      CD34_antigen; CD34/Podocalyxin family

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049267.1 Alternate UMICH_Zoey_3.1

      Range
      6355774..6380048 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

      Range
      6458250..6482488 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

      Range
      6499295..6523438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      6297083..6321394 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28270.1 GenPept UniProtKB/Swiss-Prot:Q28270

    Gene LinkOut

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