TNFSF10 TNF superfamily member 10 [Sus scrofa (pig)] - Gene

Summary

Gene symbol: TNFSF10
Gene description: TNF superfamily member 10
See related: Ensembl:ENSSSCG00000020906
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: TRAIL
Expression: Ubiquitous expression in lung (RPKM 61.2), liver (RPKM 36.7) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	13	NC_010455.5 (111021952..111103060, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	13	NC_010455.4 (119874763..119882251)

Chromosome 13 - NC_010455.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL and Fas ligand FasL expression during follicular atresia.
Title: Changes in the expression of Fox O1 and death ligand genes during follicular atresia in porcine ovary.
The chromosomal location of the porcine TNFSF10 gene was determined by FISH of a specific BAC clone to metaphase chromosomes The chromosomal location of the porcine TNFSF10 gene was determined by FISH of a specific BAC clone to metaphase chromosomes.
Title: Molecular cloning, expression analysis and assignment of the porcine tumor necrosis factor superfamily member 10 gene (TNFSF10) to SSC13q34-->q36 by fluorescence in situ hybridization and radiation hybrid mapping.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables CD40 receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables tumor necrosis factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: tumor necrosis factor ligand superfamily member 10

Names: tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor-related apoptosis-inducing ligand

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001024696.1 → NP_001019867.1 tumor necrosis factor ligand superfamily member 10

See identical proteins and their annotated locations for NP_001019867.1

Status: PROVISIONAL

Source sequence(s)

AY639873

UniProtKB/TrEMBL

A0A4X1V8G6, A0A5K1TVZ8, A0A8D0UKP2, A0A8D0VKX8, I3L617, Q4VSR6

Related

ENSSSCP00000043731.1, ENSSSCT00000042290.3

Conserved Domains (1) summary

pfam00229
Location:153 → 288

TNF; TNF(tumor Necrosis Factor) family

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

NC_010455.5 Reference Sscrofa11.1 Primary Assembly

Range

111021952..111103060 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021068572.1 → XP_020924231.1 tumor necrosis factor ligand superfamily member 10 isoform X1

UniProtKB/TrEMBL

A0A4X1V8G6, A0A5K1TVZ8, A0A8D0UKP2, A0A8D0VKX8, I3L617, Q4VSR6

Conserved Domains (1) summary

pfam00229
Location:153 → 288

TNF; TNF(tumor Necrosis Factor) family