ADIPOQ adiponectin, C1Q and collagen domain containing [Gallus gallus (chicken)] - Gene

Summary

Symbol: ADIPOQprovided by CGNC
Full Name: adiponectin, C1Q and collagen domain containingprovided by CGNC
Primary source: CGNC:4139
See related: Ensembl:ENSGALG00010025618
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	9	NC_052540.1 (4886000..4890655, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	9	NC_052581.1 (4719519..4724152, complement)

Chromosome 9 - NC_052540.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Adiponectin/adiponectin receptors mRNA expression profiles in chickens and their response to feed restriction.
Title: Adiponectin/adiponectin receptors mRNA expression profiles in chickens and their response to feed restriction.
Adiponectin is secreted by theca layer cells isolated from chicken ovarian follicles.
Title: Adiponectin is secreted by theca layer cells isolated from chicken ovarian follicles.
Adiponectin and the ADIPOR1 and ADIPOR2 genes are ubiquitously expressed in various tissues of Tibetan chicken and the expression of the adiponectin system is gender-dependant at certain ages in adipose tissue and skeletal muscle.
Title: Expression profiles and associations of adiponectin and adiponectin receptors with intramuscular fat in Tibetan chicken.
Adiponectin impairs chicken preadipocytes differentiation through p38 MAPK/ATF-2 and TOR/p70 S6 kinase pathways.
Title: Adiponectin impairs chicken preadipocytes differentiation through p38 MAPK/ATF-2 and TOR/p70 S6 kinase pathways.
These results indicated that rosiglitazone and dexamethasone could regulate adiponectin expression in muscle of broilers and adiponectin had an anti-lipogenic effect by p38 MAPK/ATF2 signaling pathway.
Title: Adiponectin decreases lipids deposition by p38 MAPK/ATF2 signaling pathway in muscle of broilers.
Globular adiponectin (gAd) activated the phosphorylation levels of p38 mitogen-activated protein kinase (p38 MAPK) and activating transcription factor 2 (ATF-2), and suppressed the phosphorylation levels of rapamycin (TOR) and p70 S6 Kinase (P < 0.01).
Title: Recombinant globular adiponectin inhibits lipid deposition by p38 MAPK/ATF-2 and TOR/p70 S6 kinase pathways in chicken adipocytes.
Dietary energy and protein levels had no significant effect on adiponectin gene expression in abdominal adipose tissue in broilers.
Title: Evaluation of adiponectin gene expression in the abdominal adipose tissue of broiler chickens: feed restriction, dietary energy, and protein influences adiponectin messenger ribonucleic acid expression.
plasma adiponectin levels were significantly lower in 8- compared with 4-wk-old male chickens & inversely related to abdominal fat pad mass; results provide novel evidence that adiponectin in chicken plasma and tissues is predominantly a HMW multimer
Title: Unique profile of chicken adiponectin, a predominantly heavy molecular weight multimer, and relationship to visceral adiposity.
in chicken, adiponectin, mainly expressed in theca cells, could exert paracrine or autocrine effect on the ovarian steroidogenesis
Title: Expression of adiponectin and its receptors (AdipoR1 and AdipoR2) in chicken ovary: potential role in ovarian steroidogenesis.
This gene is involved in adipocyte differentiation in mammals and may play similar roles in chickens.
Title: cDNA cloning, genomic structure, chromosomal mapping and expression analysis of ADIPOQ (adiponectin) in chicken.

Submit: New GeneRIF Correction See all GeneRIFs (11)

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: adiponectin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_206991.2 → NP_996874.1 adiponectin precursor

See identical proteins and their annotated locations for NP_996874.1

Status: VALIDATED

Source sequence(s)

JAENSK010000240

UniProtKB/TrEMBL

Q4VKW2, Q6QWE7

Related

ENSGALP00010038662.1, ENSGALT00010062526.1

Conserved Domains (2) summary

smart00110
Location:104 → 240

C1Q; Complement component C1q domain

pfam01391
Location:40 → 90

Collagen; Collagen triple helix repeat (20 copies)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

4886000..4890655 complement

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GenBank, FASTA, Sequence Viewer (Graphics)