ASIP agouti signaling protein [Bos taurus (cattle)] - Gene

Summary

Official Symbol: ASIPprovided by VGNC
Official Full Name: agouti signaling proteinprovided by VGNC
Primary source: VGNC:VGNC:26214
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	13	NC_037340.1 (63639821..63668127)

Chromosome 13 - NC_037340.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Our results provide evidence for a widespread expression of ASIP in bovine tissues at mRNA and, for the first time, at protein level.
Title: Agouti revisited: transcript quantification of the ASIP gene in bovine tissues related to protein expression and localization.
Possible consequences of Abr (agouti gene mutated by insertion of LINE element)for meat and milk production in cattle.
Title: The insertion of a full-length Bos taurus LINE element is responsible for a transcriptional deregulation of the Normande Agouti gene.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables melanocortin receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables neuropeptide hormone activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in hormone-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in melanosome organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of melanin biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: agouti-signaling protein

Names: ASP; agouti signal peptide; agouti signaling protein, nonagouti homolog; agouti switch protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.