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    TGM2 transglutaminase 2 [ Gallus gallus (chicken) ]

    Gene ID: 396432, updated on 5-Mar-2024

    Summary

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    Symbol
    TGM2provided by CGNC
    Full Name
    transglutaminase 2provided by CGNC
    Primary source
    CGNC:49801
    See related
    Ensembl:ENSGALG00010015676
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    TGL2
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 20
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 20 NC_052551.1 (10709856..10719810)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 20 NC_052592.1 (10497260..10507226)

    Chromosome 20 - NC_052551.1Genomic Context describing neighboring genes Neighboring gene lipopolysaccharide binding protein Neighboring gene KIAA1755 ortholog Neighboring gene regulation of nuclear pre-mRNA domain containing 1B Neighboring gene TELO2 interacting protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of tissue transglutaminase in the developing chicken limb is associated both with apoptosis and endochondral ossification. Thomázy VA, et al. Cell Death Differ, 1999 Feb. PMID 10200561
    2. Cloning and expression of chicken erythrocyte transglutaminase. Weraarchakul-Boonmark N, et al. Proc Natl Acad Sci U S A, 1992 Oct 15. PMID 1357669, Free PMC Article
    3. Lateral growth limitation of corneal fibrils and their lamellar stacking depend on covalent collagen cross-linking by transglutaminase-2 and lysyl oxidases, respectively. Wang L, et al. J Biol Chem, 2014 Jan 10. PMID 24265319, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data indicate that covalent collagen cross-links are formed by both lysyl oxidases and tissue transglutaminase-2.
      Title: Lateral growth limitation of corneal fibrils and their lamellar stacking depend on covalent collagen cross-linking by transglutaminase-2 and lysyl oxidases, respectively.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein-glutamine gamma-glutamyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptide cross-linking IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein-glutamine gamma-glutamyltransferase 2
    Names
    TG(C)
    TGC
    TGase C
    TGase-2
    erythrocyte transglutaminase
    isopeptidase TGM2
    protein-glutamine deamidase TGM2
    protein-glutamine dopaminyltransferase TGM2
    protein-glutamine histaminyltransferase TGM2
    protein-glutamine noradrenalinyltransferase TGM2
    protein-glutamine serotonyltransferase TGM2
    tissue transglutaminase
    transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
    transglutaminase C
    NP_001378925.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001391996.2 → NP_001378925.2  protein-glutamine gamma-glutamyltransferase 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000328
      UniProtKB/TrEMBL
      A0A8V0YZN0, O13265
      Related
      ENSGALP00010021804.1, ENSGALT00010037749.1
      Conserved Domains (1) summary
      smart00460
      Location:270 → 362
      TGc; Transglutaminase/protease-like homologues

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052551.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      10709856..10719810
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052592.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      10497260..10507226
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_205448.1: Suppressed sequence

      Description
      NM_205448.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q01841.3 GenPept UniProtKB/Swiss-Prot:Q01841

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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