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    imp3 IMP U3 small nucleolar ribonucleoprotein 3 [ Danio rerio (zebrafish) ]

    Gene ID: 393237, updated on 27-Mar-2024

    Summary

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    Official Symbol
    imp3provided by ZNC
    Official Full Name
    IMP U3 small nucleolar ribonucleoprotein 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1062
    See related
    Ensembl:ENSDARG00000115266 AllianceGenome:ZFIN:ZDB-GENE-040426-1062
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56526
    Summary
    Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing. Part of Mpp10 complex. Orthologous to human IMP3 (IMP U3 small nucleolar ribonucleoprotein 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (9983076..9989947, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (10185256..10192127, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene TSEN15 tRNA splicing endonuclease subunit Neighboring gene zgc:55943 Neighboring gene SEC22 homolog B, vesicle trafficking protein a Neighboring gene solute carrier family 35 member A3b Neighboring gene family with sequence similarity 78 member Ba

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Sas10 controls ribosome biogenesis by stabilizing Mpp10 and delivering the Mpp10-Imp3-Imp4 complex to nucleolus. Zhao S, et al. Nucleic Acids Res, 2019 Apr 8. PMID 30773582, Free PMC Article
    2. Characterization of genetic loss-of-function of Fus in zebrafish. Lebedeva S, et al. RNA Biol, 2017 Jan 2. PMID 27898262, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC56526

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Mpp10 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Mpp10 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    U3 small nucleolar ribonucleoprotein protein IMP3
    Names
    IMP3, U3 small nucleolar ribonucleoprotein, homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291357.1 → NP_001278286.1  U3 small nucleolar ribonucleoprotein protein IMP3

      Status: VALIDATED

      Source sequence(s)
      EH466588, EH493453, EH598772
      UniProtKB/TrEMBL
      A0A2R8QAU3, A0A8M1P6M9
      Related
      ENSDARP00000148639.1, ENSDART00000184369.1
      Conserved Domains (3) summary
      COG0522
      Location:1 → 177
      RpsD; Ribosomal protein S4 or related protein [Translation, ribosomal structure and biogenesis]
      pfam00163
      Location:5 → 55
      Ribosomal_S4; Ribosomal protein S4/S9 N-terminal domain
      pfam01479
      Location:108 → 154
      S4; S4 domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      9983076..9989947 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_200267.1: Suppressed sequence

      Description
      NM_200267.1: This RefSeq was permanently suppressed because it was based on a chimeric sequence.
    Nucleotide Protein Strain
    Heading Accession and Version

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