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    QKI QKI, KH domain containing RNA binding [ Gallus gallus (chicken) ]

    Gene ID: 374204, updated on 3-Apr-2024

    Summary

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    Symbol
    QKIprovided by CGNC
    Full Name
    QKI, KH domain containing RNA bindingprovided by CGNC
    Primary source
    CGNC:8781
    See related
    Ensembl:ENSGALG00010006041
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (43784462..43923838, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (43690995..43830374, complement)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112532166 Neighboring gene uncharacterized LOC107053062 Neighboring gene uncharacterized LOC121110378 Neighboring gene PARK2 coregulated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Four isoforms of the signal-transduction and RNA-binding protein QKI expressed during chicken spermatogenesis. Mezquita J, et al. Mol Reprod Dev, 1998 May. PMID 9547512
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    KH domain-containing RNA-binding protein QKI; protein quaking
    Names
    RNA binding/signal transduction protein QkI-2
    homolog of mouse quaking QKI (KH domain RNA binding protein)
    quaking homolog, KH domain RNA binding

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204310.3 → NP_989641.2  KH domain-containing RNA-binding protein QKI

      See identical proteins and their annotated locations for NP_989641.2

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000063
      UniProtKB/Swiss-Prot
      Q9PST2, Q9YH18, Q9YH19, Q9YH20
      UniProtKB/TrEMBL
      A0A8V0XP69
      Related
      ENSGALP00010008493.1, ENSGALT00010014472.1
      Conserved Domains (4) summary
      PHA03247
      Location:212 → 313
      PHA03247; large tegument protein UL36; Provisional
      cd02395
      Location:83 → 205
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      pfam16551
      Location:313 → 340
      Quaking_NLS; Putative nuclear localization signal of quaking

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      43784462..43923838 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015284003.4 → XP_015139489.1  protein quaking isoform X8

      UniProtKB/TrEMBL
      A0A8V0XP69
      Conserved Domains (4) summary
      PRK14950
      Location:195 → 304
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      pfam16551
      Location:303 → 332
      Quaking_NLS; Putative nuclear localization signal of quaking
      cd22465
      Location:81 → 183
      KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

    2. XM_040696716.2 → XP_040552650.1  protein quaking isoform X5

      UniProtKB/TrEMBL
      A0A8V0XP69
      Related
      ENSGALP00010008491.1, ENSGALT00010014469.1
      Conserved Domains (1) summary
      COG5176
      Location:83 → 206
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    3. XM_040696715.2 → XP_040552649.1  protein quaking isoform X14

      UniProtKB/TrEMBL
      A0A8V0XP69
      Conserved Domains (2) summary
      COG5176
      Location:83 → 221
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]
      PRK14950
      Location:210 → 319
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional

    4. XM_015284000.4 → XP_015139486.1  protein quaking isoform X3

      UniProtKB/TrEMBL
      A0A8V0XP69
      Conserved Domains (4) summary
      cd02395
      Location:83 → 220
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
      pfam07777
      Location:247 → 292
      MFMR; G-box binding protein MFMR
      pfam16544
      Location:10 → 68
      STAR_dimer; Homodimerization region of STAR domain protein
      pfam16551
      Location:328 → 355
      Quaking_NLS; Putative nuclear localization signal of quaking

    5. XM_015284001.4 → XP_015139487.1  protein quaking isoform X4

      UniProtKB/TrEMBL
      A0A8V0XP69
      Conserved Domains (4) summary
      PRK14950
      Location:212 → 321
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional
      cd02395
      Location:83 → 222
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      pfam16551
      Location:322 → 349
      Quaking_NLS; Putative nuclear localization signal of quaking

    6. XM_015283999.4 → XP_015139485.1  protein quaking isoform X2

      UniProtKB/TrEMBL
      A0A8V0XP69
      Conserved Domains (3) summary
      cd02395
      Location:83 → 222
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      pfam16551
      Location:329 → 356
      Quaking_NLS; Putative nuclear localization signal of quaking

    7. XM_015283998.4 → XP_015139484.1  protein quaking isoform X1

      UniProtKB/TrEMBL
      A0A8V0XP69
      Conserved Domains (4) summary
      PHA03247
      Location:229 → 330
      PHA03247; large tegument protein UL36; Provisional
      cd02395
      Location:83 → 222
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      pfam16551
      Location:330 → 357
      Quaking_NLS; Putative nuclear localization signal of quaking

    8. XM_040696721.2 → XP_040552655.1  protein quaking isoform X12

      UniProtKB/TrEMBL
      A0A8V0XWS7
      Conserved Domains (2) summary
      COG5176
      Location:83 → 206
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]
      PRK14950
      Location:195 → 288
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional

    9. XM_040696720.2 → XP_040552654.1  protein quaking isoform X11

      UniProtKB/TrEMBL
      A0A8V0XWS7
      Conserved Domains (3) summary
      pfam07777
      Location:210 → 276
      MFMR; G-box binding protein MFMR
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      cd22465
      Location:81 → 183
      KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

    10. XM_040696722.2 → XP_040552656.1  protein quaking isoform X13

      UniProtKB/TrEMBL
      A0A8V0XWS7
      Conserved Domains (1) summary
      COG5176
      Location:83 → 206
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    11. XM_040696719.2 → XP_040552653.1  protein quaking isoform X10

      UniProtKB/TrEMBL
      A0A8V0XWS7
      Conserved Domains (2) summary
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      cd22465
      Location:81 → 183
      KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

    12. XM_015284004.4 → XP_015139490.1  protein quaking isoform X9

      UniProtKB/TrEMBL
      A0A8V0XJY9, A0A8V0XU17
      Related
      ENSGALP00010008488.1, ENSGALT00010014464.1
      Conserved Domains (3) summary
      cd02395
      Location:83 → 222
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
      pfam07777
      Location:241 → 286
      MFMR; G-box binding protein MFMR
      pfam16544
      Location:10 → 68
      STAR_dimer; Homodimerization region of STAR domain protein

    13. XM_040696717.2 → XP_040552651.1  protein quaking isoform X7

      UniProtKB/TrEMBL
      A0A8V0XJY9
      Conserved Domains (1) summary
      COG5176
      Location:83 → 223
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    14. XM_015284002.4 → XP_015139488.1  protein quaking isoform X6

      UniProtKB/TrEMBL
      A0A8V0XJY9
      Related
      ENSGALP00010008485.1, ENSGALT00010014460.1
      Conserved Domains (2) summary
      cd02395
      Location:83 → 222
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      43690995..43830374 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046912900.1 → XP_046768856.1  protein quaking isoform X8

    2. XM_046912897.1 → XP_046768853.1  protein quaking isoform X5

    3. XM_046912895.1 → XP_046768851.1  protein quaking isoform X3

    4. XM_046912896.1 → XP_046768852.1  protein quaking isoform X4

    5. XM_046912894.1 → XP_046768850.1  protein quaking isoform X2

    6. XM_046912893.1 → XP_046768849.1  protein quaking isoform X1

    7. XM_046912904.1 → XP_046768860.1  protein quaking isoform X12

    8. XM_046912903.1 → XP_046768859.1  protein quaking isoform X11

    9. XM_046912905.1 → XP_046768861.1  protein quaking isoform X13

    10. XM_046912902.1 → XP_046768858.1  protein quaking isoform X10

    11. XM_046912901.1 → XP_046768857.1  protein quaking isoform X9

      UniProtKB/TrEMBL
      A0A8V0XU17

    12. XM_046912899.1 → XP_046768855.1  protein quaking isoform X7

    13. XM_046912898.1 → XP_046768854.1  protein quaking isoform X6

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9YH18.2 GenPept UniProtKB/Swiss-Prot:Q9YH18

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