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    l1cam.S L1 cell adhesion molecule S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 373742, updated on 11-Apr-2024

    Summary

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    Official Symbol
    l1cam.S
    Official Full Name
    L1 cell adhesion molecule S homeolog
    Primary source
    Xenbase:XB-GENE-5914737
    Locus tag
    XELAEV_18041783mg
    See related
    EnsemblRapid:ENSXLAG00005015049
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    l1cam; l1cam-a
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    Genomic context

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    Location:
    chromosome: 8S
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (38468841..38588829)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (38007643..38128336)

    Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene opsin 1, short wave sensitive gene 2 S homeolog Neighboring gene red-sensitive opsin-like Neighboring gene arginine vasopressin receptor 2 S homeolog Neighboring gene PDZ domain containing 4 S homeolog Neighboring gene small nucleolar RNA SNORA42/SNORA80 family Neighboring gene signal sequence receptor, delta S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC80658

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables cell-cell adhesion mediator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within brain development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    L1 cell adhesion molecule S homeolog
    Names
    neural cell adhesion molecule L1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001136163.2 → NP_001129635.2  L1 cell adhesion molecule S homeolog precursor

      Status: PROVISIONAL

      Source sequence(s)
      BC073282
      UniProtKB/TrEMBL
      A0A8J0QEL3, Q6GP61
      Related
      ENSXLAP00005044083.1, ENSXLAT00005045155.1
      Conserved Domains (9) summary
      cd05733
      Location:53 → 129
      Ig6_L1-CAM_like; Sixth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins
      cd05845
      Location:132 → 226
      Ig2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins
      smart00060
      Location:611 → 694
      FN3; Fibronectin type 3 domain
      smart00410
      Location:432 → 512
      IG_like; Immunoglobulin like
      cd00063
      Location:908 → 995
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:517 → 607
      I-set; Immunoglobulin I-set domain
      pfam00041
      Location:811 → 896
      fn3; Fibronectin type III domain
      pfam13882
      Location:1137 → 1222
      Bravo_FIGEY; Bravo-like intracellular region
      cl11960
      Location:258 → 328
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      38468841..38588829
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018231827.2 → XP_018087316.1  L1 cell adhesion molecule S homeolog isoform X2

      UniProtKB/TrEMBL
      A0A1L8F1V6, A0A974C2U2, Q6GP61
      Related
      ENSXLAP00005044128.1, ENSXLAT00005045200.1

    2. XM_041574064.1 → XP_041429998.1  L1 cell adhesion molecule S homeolog isoform X5

      UniProtKB/TrEMBL
      A0A8J1LK84, Q6GP61
      Related
      ENSXLAP00005044124.1, ENSXLAT00005045196.1
      Conserved Domains (6) summary
      smart00060
      Location:616 → 699
      FN3; Fibronectin type 3 domain
      smart00409
      Location:437 → 517
      IG; Immunoglobulin
      smart00410
      Location:147 → 214
      IG_like; Immunoglobulin like
      cd00063
      Location:913 → 1000
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:353 → 357
      Ig; Ig strand B [structural motif]
      cl11960
      Location:338 → 420
      Ig; Immunoglobulin domain

    3. XM_018231824.2 → XP_018087313.1  L1 cell adhesion molecule S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A8J0TN46, Q6GP61
      Conserved Domains (9) summary
      smart00060
      Location:616 → 699
      FN3; Fibronectin type 3 domain
      cd00063
      Location:816 → 908
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:914 → 1000
      fn3; Fibronectin type III domain
      pfam13882
      Location:1142 → 1227
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:428 → 504
      Ig_3; Immunoglobulin domain
      cd00096
      Location:263 → 267
      Ig; Ig strand B [structural motif]
      cd05733
      Location:40 → 134
      IgI_L1-CAM_like; Immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      cd05845
      Location:143 → 233
      IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
      cl11960
      Location:251 → 333
      Ig; Immunoglobulin domain

    4. XM_018231828.2 → XP_018087317.1  L1 cell adhesion molecule S homeolog isoform X3

      UniProtKB/TrEMBL
      A0A8J0TM89, Q6GP61

    5. XM_018231829.2 → XP_018087318.1  L1 cell adhesion molecule S homeolog isoform X4

      UniProtKB/TrEMBL
      A0A1L8F1Q7, A0A974C326, Q6GP61

    6. XM_041574063.1 → XP_041429997.1  L1 cell adhesion molecule S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A8J0TN46, Q6GP61
      Conserved Domains (9) summary
      smart00060
      Location:616 → 699
      FN3; Fibronectin type 3 domain
      cd00063
      Location:816 → 908
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:914 → 1000
      fn3; Fibronectin type III domain
      pfam13882
      Location:1142 → 1227
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:428 → 504
      Ig_3; Immunoglobulin domain
      cd00096
      Location:263 → 267
      Ig; Ig strand B [structural motif]
      cd05733
      Location:40 → 134
      IgI_L1-CAM_like; Immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      cd05845
      Location:143 → 233
      IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
      cl11960
      Location:251 → 333
      Ig; Immunoglobulin domain

    7. XM_018231825.2 → XP_018087314.1  L1 cell adhesion molecule S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A8J0TN46, Q6GP61
      Conserved Domains (9) summary
      smart00060
      Location:616 → 699
      FN3; Fibronectin type 3 domain
      cd00063
      Location:816 → 908
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:914 → 1000
      fn3; Fibronectin type III domain
      pfam13882
      Location:1142 → 1227
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:428 → 504
      Ig_3; Immunoglobulin domain
      cd00096
      Location:263 → 267
      Ig; Ig strand B [structural motif]
      cd05733
      Location:40 → 134
      IgI_L1-CAM_like; Immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      cd05845
      Location:143 → 233
      IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
      cl11960
      Location:251 → 333
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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