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    Golga7 golgin A7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361171, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Golga7provided by RGD
    Official Full Name
    golgin A7provided by RGD
    Primary source
    RGD:1359725
    See related
    Ensembl:ENSRNOG00000017956 AllianceGenome:RGD:1359725
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in establishment of protein localization to membrane; peptidyl-L-cysteine S-palmitoylation; and protein stabilization. Predicted to act upstream of or within Golgi to plasma membrane transport. Predicted to be located in Golgi membrane. Predicted to be intrinsic component of Golgi membrane. Predicted to be part of palmitoyltransferase complex. Predicted to be active in Golgi stack. Orthologous to human GOLGA7 (golgin A7). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 356.5), Kidney (RPKM 282.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    16q12.5
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (75469794..75485055)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (68767259..68782536)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (73564172..73579389)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1, pseudogene 35 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene GINS complex subunit 4 Neighboring gene glycerol-3-phosphate acyltransferase 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of GCP16, a novel acylated Golgi protein that interacts with GCP170. Ohta E, et al. J Biol Chem, 2003 Dec 19. PMID 14522980
    2. DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras. Swarthout JT, et al. J Biol Chem, 2005 Sep 2. PMID 16000296
    3. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article
    4. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Buschow SI, et al. Immunol Cell Biol, 2010 Nov-Dec. PMID 20458337
    5. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC93825

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi to plasma membrane protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in Golgi to plasma membrane protein transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in Golgi to plasma membrane protein transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within Golgi to plasma membrane transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in peptidyl-L-cysteine S-palmitoylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein stabilization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein stabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in Golgi stack IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi stack IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi stack ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in Golgi stack ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of palmitoyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of palmitoyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of palmitoyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of palmitoyltransferase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    golgin subfamily A member 7
    Names
    golgi autoantigen, golgin subfamily a, 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007731.1 → NP_001007732.1  golgin subfamily A member 7

      See identical proteins and their annotated locations for NP_001007732.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078959
      UniProtKB/Swiss-Prot
      Q6AYQ1
      UniProtKB/TrEMBL
      A0A8L2QIB4, A6IW41
      Conserved Domains (1) summary
      pfam10256
      Location:12 → 124
      Erf4; Golgin subfamily A member 7/ERF4 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      75469794..75485055
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063275571.1 → XP_063131641.1  golgin subfamily A member 7 isoform X2

    2. XM_017600185.3 → XP_017455674.1  golgin subfamily A member 7 isoform X1

      UniProtKB/Swiss-Prot
      Q6AYQ1
      UniProtKB/TrEMBL
      A0A8L2QIB4, A6IW41
      Related
      ENSRNOP00000033324.4
      Conserved Domains (1) summary
      pfam10256
      Location:12 → 124
      Erf4; Golgin subfamily A member 7/ERF4 family

    3. XM_039094672.2 → XP_038950600.1  golgin subfamily A member 7 isoform X1

      UniProtKB/Swiss-Prot
      Q6AYQ1
      UniProtKB/TrEMBL
      A0A8L2QIB4, A6IW41
      Conserved Domains (1) summary
      pfam10256
      Location:12 → 124
      Erf4; Golgin subfamily A member 7/ERF4 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AYQ1.1 GenPept UniProtKB/Swiss-Prot:Q6AYQ1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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