taf5l TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: taf5lprovided by ZNC
Official Full Name: TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factorprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5987
See related: Ensembl:ENSDARG00000025808 AllianceGenome:ZFIN:ZDB-GENE-030131-5987
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fi28g02; zgc:63765; wu:fi28g02
Summary: Predicted to enable transcription coactivator activity. Predicted to be involved in histone acetylation and regulation of transcription, DNA-templated. Predicted to be located in SAGA complex. Predicted to be part of histone acetyltransferase complex. Orthologous to human TAF5L (TATA-box binding protein associated factor 5 like). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (53911840..53918778, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (53252097..53259035, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables transcription coactivator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of histone acetyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of nuclear protein-containing complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
NOT part_of transcription factor TFIID complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199852.1 → NP_956146.1 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

See identical proteins and their annotated locations for NP_956146.1

Status: PROVISIONAL

Source sequence(s)

BC056820

UniProtKB/TrEMBL

Q6PGV3

Related

ENSDARP00000038258.4, ENSDART00000032552.6

Conserved Domains (4) summary

cd08044
Location:66 → 200

TAF5_NTD2; TAF5_NTD2 is the second conserved N-terminal region of TATA Binding Protein (TBP) Associated Factor 5 (TAF5), involved in forming Transcription Factor IID (TFIID)

COG2319
Location:227 → 581

WD40; WD40 repeat [General function prediction only]

cd00200
Location:289 → 593

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:357 → 394

7WD40; WD40 repeat [structural motif]