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    rcan3 regulator of calcineurin 3 [ Danio rerio (zebrafish) ]

    Gene ID: 325356, updated on 27-Mar-2024

    Summary

    Official Symbol
    rcan3provided by ZNC
    Official Full Name
    regulator of calcineurin 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-445
    See related
    Ensembl:ENSDARG00000032623 AllianceGenome:ZFIN:ZDB-GENE-040718-445
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    dscr1l2; zgc:91820; wu:fc68f05; zgc:113155
    Summary
    Predicted to enable calcium-dependent protein serine/threonine phosphatase regulator activity. Predicted to be involved in calcium-mediated signaling. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system; otic placode; otic vesicle; paraxial mesoderm; and retina. Orthologous to human RCAN3 (RCAN family member 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 17
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (26879725..26926577, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (26861334..26908186, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene si:dkey-221l4.10 Neighboring gene jade family PHD finger 1 Neighboring gene NIPA like domain containing 3 Neighboring gene grainyhead-like transcription factor 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium-dependent protein serine/threonine phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in calcium-mediated signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within calcium-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    calcipressin-3
    Names
    Down syndrome critical region gene 1-like 2
    regulator of calcineurin family member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005392.1NP_001005392.1  calcipressin-3

      See identical proteins and their annotated locations for NP_001005392.1

      Status: PROVISIONAL

      Source sequence(s)
      BC076514
      UniProtKB/TrEMBL
      A0A8M1N230, Q6DG39
      Related
      ENSDARP00000050201.4, ENSDART00000050202.6
      Conserved Domains (1) summary
      pfam04847
      Location:57222
      Calcipressin; Calcipressin

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      26879725..26926577 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005158490.3XP_005158547.1  calcipressin-3 isoform X1

      See identical proteins and their annotated locations for XP_005158547.1

      UniProtKB/TrEMBL
      A0A8M2B4V5, Q5CZS1
      Related
      ENSDARP00000045841.3, ENSDART00000045842.4
      Conserved Domains (1) summary
      pfam04847
      Location:22187
      Calcipressin; Calcipressin

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394994.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      116373..161852 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)