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    ZNF875 zinc finger protein 875 [ Homo sapiens (human) ]

    Gene ID: 284459, updated on 11-Apr-2024

    Summary

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    Official Symbol
    ZNF875provided by HGNC
    Official Full Name
    zinc finger protein 875provided by HGNC
    Primary source
    HGNC:HGNC:4928
    See related
    Ensembl:ENSG00000181666 MIM:165250; AllianceGenome:HGNC:4928
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HKR1
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in prostate (RPKM 5.1), thyroid (RPKM 4.9) and 25 other tissues See more
    Orthologs
    all
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    Genomic context

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    Location:
    19q13.12
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (37312837..37364455)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (40114360..40165968)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (37803739..37855357)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1535 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:37763986-37764523 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:37764524-37765060 Neighboring gene Putative uncharacterized protein PP6455 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:37771594-37772125 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:37772126-37772656 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:37777707-37778689 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:37787960-37788471 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10554 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14541 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:37809147-37810044 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr19:37811117-37811765 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr19:37811766-37812414 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:37824558-37825500 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:37825501-37826442 Neighboring gene MPRA-validated peak3463 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14544 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14545 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14546 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10555 Neighboring gene zinc finger protein 527 Neighboring gene zinc finger protein 569 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14547 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14548 Neighboring gene zinc finger protein 570

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. The Krüppel-type zinc finger family gene, HKR1, is induced in lung cancer by exposure to platinum drugs. Oguri T, et al. Gene, 1998 Nov 5. PMID 9813242
    2. Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians. Zeng Q, et al. BMC Med Genomics, 2018 Feb 2. PMID 29394898, Free PMC Article
    3. Assignment of the human GLI2 gene to 2q14 by fluorescence in situ hybridization. Matsumoto N, et al. Genomics, 1996 Aug 15. PMID 8812445
    4. The GLI-Kruppel family of human genes. Ruppert JM, et al. Mol Cell Biol, 1988 Aug. PMID 2850480, Free PMC Article
    5. Scaffold Protein Ahk1, Which Associates with Hkr1, Sho1, Ste11, and Pbs2, Inhibits Cross Talk Signaling from the Hkr1 Osmosensor to the Kss1 Mitogen-Activated Protein Kinase. Nishimura A, et al. Mol Cell Biol, 2016 Jan 19. PMID 26787842, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the methylation profile combination of HKR1, ROD1, and NLRC5 could be a promising biomarker for aging in Hainan centenarians
      Title: Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians.
    2. Ahk1 is a scaffold protein in the HKR1 subbranch and prevents incorrect signal flow from Hkr1 to Kss1
      Title: Scaffold Protein Ahk1, Which Associates with Hkr1, Sho1, Ste11, and Pbs2, Inhibits Cross Talk Signaling from the Hkr1 Osmosensor to the Kss1 Mitogen-Activated Protein Kinase.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ41385

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 875
    Names
    HKR1, GLI-Kruppel zinc finger family member
    Krueppel-related zinc finger protein 1
    oncogene HKR1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001329761.2 → NP_001316690.1  zinc finger protein 875 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), as well as variant 3, encodes isoform b.
      Source sequence(s)
      AC008806, AC016590
      Consensus CDS
      CCDS82337.1
      UniProtKB/TrEMBL
      K7EPW3
      Related
      ENSP00000467562.1, ENST00000589392.5

    2. NM_001329762.2 → NP_001316691.1  zinc finger protein 875 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variant 2, encodes isoform b.
      Source sequence(s)
      AC008806, AC016590
      Consensus CDS
      CCDS82337.1
      UniProtKB/TrEMBL
      K7EPW3

    3. NM_001329763.2 → NP_001316692.1  zinc finger protein 875 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variant 5, encodes isoform c.
      Source sequence(s)
      AC008806, AC016590
      Consensus CDS
      CCDS82338.1
      UniProtKB/Swiss-Prot
      P10072
      Conserved Domains (3) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box
      COG5048
      Location:280 → 639
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:368 → 388
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. NM_001329764.2 → NP_001316693.1  zinc finger protein 875 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5), as well as variant 4, encodes isoform c.
      Source sequence(s)
      AC008806, AC016590
      Consensus CDS
      CCDS82338.1
      UniProtKB/Swiss-Prot
      P10072
      Conserved Domains (3) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box
      COG5048
      Location:280 → 639
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:368 → 388
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. NM_001329765.2 → NP_001316694.1  zinc finger protein 875 isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6), as well as variant 7, encodes isoform d.
      Source sequence(s)
      AC008806, AC016590

    6. NM_001329766.2 → NP_001316695.1  zinc finger protein 875 isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variant 6, encodes isoform d.
      Source sequence(s)
      AC008806, AC016590

    7. NM_001329767.2 → NP_001316696.1  zinc finger protein 875 isoform e

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    8. NM_001329768.2 → NP_001316697.1  zinc finger protein 875 isoform f

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    9. NM_001329769.2 → NP_001316698.1  zinc finger protein 875 isoform g

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    10. NM_001329770.2 → NP_001316699.1  zinc finger protein 875 isoform h

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    11. NM_001329771.2 → NP_001316700.1  zinc finger protein 875 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12), as well as variants 13 and 14, encodes isoform i.
      Source sequence(s)
      AC008806, AC016590

    12. NM_001329772.2 → NP_001316701.1  zinc finger protein 875 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (13), as well as variants 12 and 14, encodes isoform i.
      Source sequence(s)
      AC008806, AC016590

    13. NM_001329773.2 → NP_001316702.1  zinc finger protein 875 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (14), as well as variants 12 and 13, encodes isoform i.
      Source sequence(s)
      AC008806, AC016590

    14. NM_001329774.2 → NP_001316703.1  zinc finger protein 875 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (15), as well as variants 16-19, encodes isoform j.
      Source sequence(s)
      AC008806, AC016590
      Consensus CDS
      CCDS82339.1
      UniProtKB/TrEMBL
      Q7Z6E1
      Conserved Domains (3) summary
      COG5048
      Location:238 → 597
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:326 → 346
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    15. NM_001329775.2 → NP_001316704.1  zinc finger protein 875 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (16), as well as variants 15 and 17-19, encodes isoform j.
      Source sequence(s)
      AC008806, AC016590
      Consensus CDS
      CCDS82339.1
      UniProtKB/TrEMBL
      Q7Z6E1
      Conserved Domains (3) summary
      COG5048
      Location:238 → 597
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:326 → 346
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    16. NM_001329776.2 → NP_001316705.1  zinc finger protein 875 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (17), as well as variants 15, 16, 18, and 19, encodes isoform j.
      Source sequence(s)
      AC008806, AC016590
      Consensus CDS
      CCDS82339.1
      UniProtKB/TrEMBL
      Q7Z6E1
      Related
      ENSP00000438261.1, ENST00000541583.6
      Conserved Domains (3) summary
      COG5048
      Location:238 → 597
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:326 → 346
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    17. NM_001329777.2 → NP_001316706.1  zinc finger protein 875 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (18), as well as variants 15-17 and 19, encodes isoform j.
      Source sequence(s)
      AC008806, AC016590
      Consensus CDS
      CCDS82339.1
      UniProtKB/TrEMBL
      Q7Z6E1
      Conserved Domains (3) summary
      COG5048
      Location:238 → 597
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:326 → 346
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    18. NM_001329778.2 → NP_001316707.1  zinc finger protein 875 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (19), as well as variants 15-18, encodes isoform j.
      Source sequence(s)
      AC008806, AC016590
      Consensus CDS
      CCDS82339.1
      UniProtKB/TrEMBL
      Q7Z6E1
      Conserved Domains (3) summary
      COG5048
      Location:238 → 597
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:326 → 346
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    19. NM_001329779.2 → NP_001316708.1  zinc finger protein 875 isoform k

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    20. NM_001353803.2 → NP_001340732.1  zinc finger protein 875 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590
      Consensus CDS
      CCDS82338.1
      Related
      ENSP00000375994.3, ENST00000392153.8
      Conserved Domains (3) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box
      COG5048
      Location:280 → 639
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:368 → 388
      ZF_C2H2; C2H2 Zn finger [structural motif]

    21. NM_001353804.2 → NP_001340733.1  zinc finger protein 875 isoform l

      Status: VALIDATED

      Description
      Transcript Variant: This variant (50) lacks an exon in the 5' region and differs in the 3' coding region and 3' UTR compared to variant 1. The encoded isoform (l) differs in the N- and C-termini compared to isoform a.
      Source sequence(s)
      BC010024, DC362408
      Consensus CDS
      CCDS86758.1
      UniProtKB/TrEMBL
      K7EME6
      Related
      ENSP00000466472.1, ENST00000591259.5
      Conserved Domains (1) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box

    22. NM_181786.4 → NP_861451.1  zinc finger protein 875 isoform a

      See identical proteins and their annotated locations for NP_861451.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a).
      Source sequence(s)
      BC017256, DC362408
      Consensus CDS
      CCDS12502.1
      UniProtKB/Swiss-Prot
      A8MRS7, P10072, Q6PJD0, Q9BSW9, Q9UM09
      Related
      ENSP00000315505.3, ENST00000324411.8
      Conserved Domains (3) summary
      smart00349
      Location:33 → 92
      KRAB; krueppel associated box
      COG5048
      Location:299 → 658
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:387 → 407
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RNA

    1. NR_138103.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016590, AK128116, BC017256

    2. NR_138104.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    3. NR_138105.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    4. NR_138106.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    5. NR_138107.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    6. NR_138108.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    7. NR_138109.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590
      Related
      ENST00000652615.1

    8. NR_138110.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    9. NR_138111.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    10. NR_138112.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    11. NR_138113.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    12. NR_138114.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    13. NR_138115.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    14. NR_138116.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    15. NR_138117.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    16. NR_138118.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    17. NR_138119.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    18. NR_138120.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    19. NR_138121.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    20. NR_138122.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    21. NR_138123.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    22. NR_138124.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    23. NR_138125.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    24. NR_138126.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    25. NR_138127.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    26. NR_138128.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    27. NR_138129.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    28. NR_138130.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008806, AC016590

    29. NR_148546.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (51) lacks the open reading frame found in coding variants and contains an alternate 3' exon structure.
      Source sequence(s)
      AC016590

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      37312837..37364455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047438686.1 → XP_047294642.1  zinc finger protein 875 isoform X6

    2. XM_047438696.1 → XP_047294652.1  zinc finger protein 875 isoform X9

      UniProtKB/TrEMBL
      F5H6A5
      Related
      ENSP00000437774.1, ENST00000544914.5

    3. XM_017026675.2 → XP_016882164.1  zinc finger protein 875 isoform X4

      Conserved Domains (3) summary
      smart00349
      Location:21 → 80
      KRAB; krueppel associated box
      COG5048
      Location:287 → 646
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:375 → 395
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_047438694.1 → XP_047294650.1  zinc finger protein 875 isoform X8

      UniProtKB/TrEMBL
      Q7Z6E1

    5. XM_047438697.1 → XP_047294653.1  zinc finger protein 875 isoform X9

      UniProtKB/TrEMBL
      F5H6A5
      Related
      ENSP00000466467.1, ENST00000591471.5

    6. XM_047438684.1 → XP_047294640.1  zinc finger protein 875 isoform X4

    7. XM_047438687.1 → XP_047294643.1  zinc finger protein 875 isoform X6

    8. XM_047438683.1 → XP_047294639.1  zinc finger protein 875 isoform X3

    9. XM_047438685.1 → XP_047294641.1  zinc finger protein 875 isoform X5

    10. XM_047438695.1 → XP_047294651.1  zinc finger protein 875 isoform X9

      UniProtKB/TrEMBL
      F5H6A5

    11. XM_017026674.2 → XP_016882163.1  zinc finger protein 875 isoform X3

      Conserved Domains (3) summary
      smart00349
      Location:21 → 80
      KRAB; krueppel associated box
      COG5048
      Location:288 → 647
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:376 → 396
      ZF_C2H2; C2H2 Zn finger [structural motif]

    12. XM_047438688.1 → XP_047294644.1  zinc finger protein 875 isoform X7

    13. XM_047438682.1 → XP_047294638.1  zinc finger protein 875 isoform X3

    14. XM_047438689.1 → XP_047294645.1  zinc finger protein 875 isoform X7

    15. XM_047438693.1 → XP_047294649.1  zinc finger protein 875 isoform X7

    16. XM_017026673.2 → XP_016882162.1  zinc finger protein 875 isoform X2

      Conserved Domains (3) summary
      smart00349
      Location:77 → 136
      KRAB; krueppel associated box
      COG5048
      Location:343 → 702
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:431 → 451
      ZF_C2H2; C2H2 Zn finger [structural motif]

    17. XM_017026672.2 → XP_016882161.1  zinc finger protein 875 isoform X1

      Conserved Domains (3) summary
      smart00349
      Location:77 → 136
      KRAB; krueppel associated box
      COG5048
      Location:344 → 703
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:432 → 452
      ZF_C2H2; C2H2 Zn finger [structural motif]

    18. XM_047438690.1 → XP_047294646.1  zinc finger protein 875 isoform X7

    19. XM_047438691.1 → XP_047294647.1  zinc finger protein 875 isoform X7

    20. XM_047438692.1 → XP_047294648.1  zinc finger protein 875 isoform X7

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      40114360..40165968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054320713.1 → XP_054176688.1  zinc finger protein 875 isoform X4

    2. XM_054320725.1 → XP_054176700.1  zinc finger protein 875 isoform X8

      UniProtKB/TrEMBL
      Q7Z6E1

    3. XM_054320728.1 → XP_054176703.1  zinc finger protein 875 isoform X9

      UniProtKB/TrEMBL
      F5H6A5

    4. XM_054320710.1 → XP_054176685.1  zinc finger protein 875 isoform X3

    5. XM_054320718.1 → XP_054176693.1  zinc finger protein 875 isoform X7

    6. XM_054320716.1 → XP_054176691.1  zinc finger protein 875 isoform X6

    7. XM_054320727.1 → XP_054176702.1  zinc finger protein 875 isoform X9

      UniProtKB/TrEMBL
      F5H6A5

    8. XM_054320714.1 → XP_054176689.1  zinc finger protein 875 isoform X4

    9. XM_054320717.1 → XP_054176692.1  zinc finger protein 875 isoform X6

    10. XM_054320712.1 → XP_054176687.1  zinc finger protein 875 isoform X3

    11. XM_054320715.1 → XP_054176690.1  zinc finger protein 875 isoform X5

    12. XM_054320726.1 → XP_054176701.1  zinc finger protein 875 isoform X9

      UniProtKB/TrEMBL
      F5H6A5

    13. XM_054320711.1 → XP_054176686.1  zinc finger protein 875 isoform X3

    14. XM_054320729.1 → XP_054176704.1  zinc finger protein 875 isoform X10

    15. XM_054320730.1 → XP_054176705.1  zinc finger protein 875 isoform X11

    16. XM_054320708.1 → XP_054176683.1  zinc finger protein 875 isoform X1

    17. XM_054320709.1 → XP_054176684.1  zinc finger protein 875 isoform X2

    18. XM_054320719.1 → XP_054176694.1  zinc finger protein 875 isoform X7

    19. XM_054320722.1 → XP_054176697.1  zinc finger protein 875 isoform X7

    20. XM_054320724.1 → XP_054176699.1  zinc finger protein 875 isoform X7

    21. XM_054320731.1 → XP_054176706.1  zinc finger protein 875 isoform X12

    22. XM_054320721.1 → XP_054176696.1  zinc finger protein 875 isoform X7

    23. XM_054320720.1 → XP_054176695.1  zinc finger protein 875 isoform X7

    24. XM_054320723.1 → XP_054176698.1  zinc finger protein 875 isoform X7

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P10072.4 GenPept UniProtKB/Swiss-Prot:P10072

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