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    LBP lipopolysaccharide binding protein [ Ovis aries (sheep) ]

    Gene ID: 101104595, updated on 3-Apr-2024

    Summary

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    Gene symbol
    LBP
    Gene description
    lipopolysaccharide binding protein
    See related
    EnsemblRapid:ENSOARG00020010427
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 13
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 13 NC_056066.1 (67203758..67240919)

    Chromosome 13 - NC_056066.1Genomic Context describing neighboring genes Neighboring gene KIAA1755 ortholog Neighboring gene bactericidal permeability increasing protein Neighboring gene uncharacterized LOC132657643 Neighboring gene uncharacterized LOC121816222 Neighboring gene U6 spliceosomal RNA Neighboring gene transfer RNA tryptophan (anticodon CCA)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056066.1 Chromosome 13 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables lipopolysaccharide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acute-phase response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to Gram-negative bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to Gram-positive bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipopolysaccharide-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in macrophage activation involved in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of macrophage activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lipopolysaccharide-binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056066.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      67203758..67240919
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_060397796.1 → XP_060253779.1  lipopolysaccharide-binding protein isoform X1

    2. XM_004014566.5 → XP_004014615.1  lipopolysaccharide-binding protein isoform X2

      UniProtKB/TrEMBL
      W5QBW5
      Related
      ENSOARP00020013178.2, ENSOART00020015932.2
      Conserved Domains (2) summary
      smart00328
      Location:33 → 256
      BPI1; BPI/LBP/CETP N-terminal domain
      pfam02886
      Location:241 → 478
      LBP_BPI_CETP_C; LBP / BPI / CETP family, C-terminal domain

    3. XM_060397797.1 → XP_060253780.1  lipopolysaccharide-binding protein isoform X3

    4. XM_042230122.1 → XP_042086056.1  lipopolysaccharide-binding protein isoform X4

      UniProtKB/TrEMBL
      W5QBW5
      Related
      ENSOARP00020036107.1, ENSOART00020055227.1
      Conserved Domains (2) summary
      smart00329
      Location:230 → 431
      BPI2; BPI/LBP/CETP C-terminal domain
      smart00328
      Location:33 → 213
      BPI1; BPI/LBP/CETP N-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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