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    Rela RELA proto-oncogene, NF-kB subunit [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100724366, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Rela
    Gene description
    RELA proto-oncogene, NF-kB subunit
    See related
    Ensembl:ENSCPOG00000020593
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947500.1 (24416510..24425754, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176377.1 (6353301..6361674, complement)

    NW_026947500.1Genomic Context describing neighboring genes Neighboring gene pecanex 3 Neighboring gene uncharacterized LOC134470885 Neighboring gene signal-induced proliferation-associated 1 Neighboring gene lysine acetyltransferase 5 Neighboring gene ribonuclease H2 subunit C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to lipopolysaccharide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in non-canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to cytokine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor p65
    Names
    v-rel reticuloendotheliosis viral oncogene homolog A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947500.1 Reference mCavPor4.1

      Range
      24416510..24425754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063227533.1 → XP_063083603.1  transcription factor p65 isoform X3

    2. XM_003468074.5 → XP_003468122.1  transcription factor p65 isoform X1

      UniProtKB/TrEMBL
      H0VZS0
      Related
      ENSCPOP00000016204.2
      Conserved Domains (2) summary
      cd07885
      Location:19 → 187
      RHD-n_RelA; N-terminal sub-domain of the Rel homology domain (RHD) of RelA
      cd01177
      Location:194 → 290
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...

    3. XM_013150773.2 → XP_013006227.1  transcription factor p65 isoform X2

      UniProtKB/TrEMBL
      A0A286XZ59
      Related
      ENSCPOP00000030595.1
      Conserved Domains (2) summary
      cd07885
      Location:10 → 178
      RHD-n_RelA; N-terminal sub-domain of the Rel homology domain (RHD) of RelA
      cd01177
      Location:185 → 281
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...

    4. XM_063227534.1 → XP_063083604.1  transcription factor p65 isoform X3

    Nucleotide Protein
    Heading Accession and Version

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