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    ACHE acetylcholinesterase [ Pan troglodytes (chimpanzee) ]

    Gene ID: 100609296, updated on 3-Apr-2024

    Summary

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    Official Symbol
    ACHEprovided by VGNC
    Official Full Name
    acetylcholinesteraseprovided by VGNC
    Primary source
    VGNC:VGNC:4245
    Locus tag
    CK820_G0040761
    See related
    Ensembl:ENSPTRG00000019514
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (110351610..110358632, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (106698452..106705470, complement)

    Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene serrate, RNA effector molecule Neighboring gene UFM1 specific peptidase 1 (inactive) Neighboring gene small ribosomal subunit protein uS14-like Neighboring gene mucin 3A, cell surface associated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetylcholinesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acetylcholine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in choline metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acetylcholinesterase
    Names
    acetylcholinesterase (Cartwright blood group)
    acetylcholinesterase (Yt blood group)
    XP_003318708.1
    XP_003318709.1
    XP_009452110.1
    XP_009452111.1
    XP_009452114.1
    XP_009452116.1
    XP_054512119.1
    XP_054512120.1
    XP_054512121.1
    XP_054512122.1
    XP_054512125.1
    XP_054512126.1
    XP_054512127.1
    XP_054512128.1
    XP_054512129.1
    XP_054512130.1
    XP_063671549.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      110351610..110358632 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054656144.2 → XP_054512119.1  acetylcholinesterase isoform X1

    2. XM_054656147.2 → XP_054512122.1  acetylcholinesterase isoform X6

    3. XM_054656146.2 → XP_054512121.1  acetylcholinesterase isoform X5

    4. XM_009453835.5 → XP_009452110.1  acetylcholinesterase isoform X3

      See identical proteins and their annotated locations for XP_009452110.1

      Conserved Domains (2) summary
      COG0657
      Location:199 → 304
      Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
      pfam00135
      Location:103 → 630
      COesterase; Carboxylesterase family

    5. XM_054656145.2 → XP_054512120.1  acetylcholinesterase isoform X2

    6. XM_009453836.3 → XP_009452111.1  acetylcholinesterase isoform X4

      See identical proteins and their annotated locations for XP_009452111.1

      Conserved Domains (2) summary
      COG0657
      Location:198 → 303
      Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
      pfam00135
      Location:102 → 629
      COesterase; Carboxylesterase family

    7. XM_054656154.2 → XP_054512129.1  acetylcholinesterase isoform X8

      UniProtKB/TrEMBL
      A0A2J8Q8T1

    8. XM_054656155.2 → XP_054512130.1  acetylcholinesterase isoform X8

      UniProtKB/TrEMBL
      A0A2J8Q8T1

    9. XM_054656150.2 → XP_054512125.1  acetylcholinesterase isoform X7

      UniProtKB/TrEMBL
      A0A2J8Q8V8, A0A6D2Y870, H2R3Y8

    10. XM_054656151.2 → XP_054512126.1  acetylcholinesterase isoform X7

      UniProtKB/TrEMBL
      A0A2J8Q8V8, A0A6D2Y870, H2R3Y8

    11. XM_054656152.2 → XP_054512127.1  acetylcholinesterase isoform X8

      UniProtKB/TrEMBL
      A0A2J8Q8T1

    12. XM_009453841.4 → XP_009452116.1  acetylcholinesterase isoform X7

      See identical proteins and their annotated locations for XP_009452116.1

      UniProtKB/TrEMBL
      A0A2J8Q8V8, A0A6D2Y870, H2R3Y8
      Conserved Domains (1) summary
      pfam00135
      Location:39 → 563
      COesterase; Carboxylesterase family

    13. XM_003318660.5 → XP_003318708.1  acetylcholinesterase isoform X8

      See identical proteins and their annotated locations for XP_003318708.1

      UniProtKB/TrEMBL
      A0A2J8Q8T1
      Conserved Domains (2) summary
      pfam00135
      Location:37 → 563
      COesterase; Carboxylesterase family
      pfam08674
      Location:578 → 611
      AChE_tetra; Acetylcholinesterase tetramerisation domain

    14. XM_003318661.6 → XP_003318709.1  acetylcholinesterase isoform X7

      See identical proteins and their annotated locations for XP_003318709.1

      UniProtKB/TrEMBL
      A0A2J8Q8V8, A0A6D2Y870, H2R3Y8
      Conserved Domains (1) summary
      pfam00135
      Location:39 → 563
      COesterase; Carboxylesterase family

    15. XM_063815479.1 → XP_063671549.1  acetylcholinesterase isoform X7

      UniProtKB/TrEMBL
      A0A2J8Q8V8, A0A6D2Y870, H2R3Y8

    16. XM_054656153.2 → XP_054512128.1  acetylcholinesterase isoform X8

      UniProtKB/TrEMBL
      A0A2J8Q8T1

    17. XM_009453839.3 → XP_009452114.1  acetylcholinesterase isoform X7

      See identical proteins and their annotated locations for XP_009452114.1

      UniProtKB/TrEMBL
      A0A2J8Q8V8, A0A6D2Y870, H2R3Y8
      Conserved Domains (1) summary
      pfam00135
      Location:39 → 563
      COesterase; Carboxylesterase family
    Nucleotide Protein
    Heading Accession and Version

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