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    SH2B1 SH2B adaptor protein 1 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

    Gene ID: 100587926, updated on 8-Mar-2024

    Summary

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    Gene symbol
    SH2B1
    Gene description
    SH2B adaptor protein 1
    See related
    EnsemblRapid:ENSNLEG00000011102
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nomascus leucogenys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Asia_NLE_v1 (GCF_006542625.1) 2 NC_044382.1 (76637650..76648332)
    102 previous assembly Nleu_3.0 (GCF_000146795.2) 2 NC_019817.1 (81717948..81728669)

    Chromosome 2 - NC_044382.1Genomic Context describing neighboring genes Neighboring gene ataxin 2 like Neighboring gene Tu translation elongation factor, mitochondrial Neighboring gene uncharacterized LOC105739458 Neighboring gene ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 Neighboring gene rabaptin, RAB GTPase binding effector protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transmembrane receptor protein tyrosine kinase adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SH2B adapter protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Asia_NLE_v1 Primary Assembly

    Genomic

    1. NC_044382.1 Reference Asia_NLE_v1 Primary Assembly

      Range
      76637650..76648332
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030799199.1 → XP_030655059.1  SH2B adapter protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A2I3HK19
      Conserved Domains (3) summary
      cd10346
      Location:518 → 614
      SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
      cd01231
      Location:246 → 378
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam08916
      Location:26 → 81
      Phe_ZIP; Phenylalanine zipper

    2. XM_030799215.1 → XP_030655075.1  SH2B adapter protein 1 isoform X3

      Related
      ENSNLEP00000013565.3, ENSNLET00000014238.4
      Conserved Domains (3) summary
      cd10346
      Location:518 → 614
      SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
      cd01231
      Location:246 → 378
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam08916
      Location:26 → 81
      Phe_ZIP; Phenylalanine zipper

    3. XM_030799222.1 → XP_030655082.1  SH2B adapter protein 1 isoform X4

      UniProtKB/TrEMBL
      G1RK08
      Conserved Domains (3) summary
      cd10346
      Location:518 → 614
      SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
      cd01231
      Location:246 → 378
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam08916
      Location:26 → 81
      Phe_ZIP; Phenylalanine zipper

    4. XM_030799187.1 → XP_030655047.1  SH2B adapter protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A2I3HK19
      Related
      ENSNLEP00000043852.1, ENSNLET00000057936.2
      Conserved Domains (3) summary
      cd10346
      Location:518 → 614
      SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
      cd01231
      Location:246 → 378
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam08916
      Location:26 → 81
      Phe_ZIP; Phenylalanine zipper

    5. XM_030799211.1 → XP_030655071.1  SH2B adapter protein 1 isoform X2

      Conserved Domains (3) summary
      cd10346
      Location:518 → 614
      SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
      cd01231
      Location:246 → 378
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam08916
      Location:26 → 81
      Phe_ZIP; Phenylalanine zipper

    6. XM_030799193.1 → XP_030655053.1  SH2B adapter protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A2I3HK19
      Conserved Domains (3) summary
      cd10346
      Location:518 → 614
      SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
      cd01231
      Location:246 → 378
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam08916
      Location:26 → 81
      Phe_ZIP; Phenylalanine zipper

    7. XM_030799206.1 → XP_030655066.1  SH2B adapter protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A2I3HK19
      Conserved Domains (3) summary
      cd10346
      Location:518 → 614
      SH2_SH2B_family; Src homology 2 (SH2) domain found in SH2B adapter protein family
      cd01231
      Location:246 → 378
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam08916
      Location:26 → 81
      Phe_ZIP; Phenylalanine zipper
    Nucleotide Protein
    Heading Accession and Version

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