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    plxna4 plexin A4 [ Anolis carolinensis (green anole) ]

    Gene ID: 100552460, updated on 8-Mar-2024

    Summary

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    Gene symbol
    plxna4
    Gene description
    plexin A4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anolis carolinensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Iguania; Dactyloidae; Anolis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    RS_2024_02 current rAnoCar3.1.pri (GCF_035594765.1) 5 NC_085845.1 (198543423..199155636, complement)
    102 previous assembly AnoCar2.0 (GCF_000090745.1) 5 NC_014780.1 (1827009..2413510, complement)

    Chromosome 5 - NC_085845.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134299677 Neighboring gene uncharacterized LOC134299191 Neighboring gene uncharacterized LOC134299273 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables semaphorin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of semaphorin receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plexin-A4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_035594765.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference rAnoCar3.1.pri

    Genomic

    1. NC_085845.1 Reference rAnoCar3.1.pri

      Range
      198543423..199155636 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003220748.4 → XP_003220796.1  plexin-A4 isoform X1

      Conserved Domains (7) summary
      cd00603
      Location:1152 → 1237
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01180
      Location:856 → 948
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1050 → 1150
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:507 → 553
      PSI; Plexin repeat
      pfam08337
      Location:1321 → 1874
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      cl15674
      Location:953 → 1048
      IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
      cl15693
      Location:37 → 509
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    2. XM_062981246.1 → XP_062837316.1  plexin-A4 isoform X2

    Nucleotide Protein
    Heading Accession and Version

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