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    rhobtb1 Rho related BTB domain containing 1 [ Danio rerio (zebrafish) ]

    Gene ID: 100537290, updated on 27-Mar-2024

    Summary

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    Official Symbol
    rhobtb1provided by ZNC
    Official Full Name
    Rho related BTB domain containing 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-130530-871
    See related
    Ensembl:ENSDARG00000079468 AllianceGenome:ZFIN:ZDB-GENE-130530-871
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Predicted to act upstream of or within small GTPase mediated signal transduction. Orthologous to human RHOBTB1 (Rho related BTB domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See rhobtb1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (7997913..8039373)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (7963948..8005712)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 6b Neighboring gene ankyrin 3b Neighboring gene uncharacterized LOC110440139 Neighboring gene transmembrane protein 26b Neighboring gene ciliary associated calcium binding coiled-coil 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    rho-related BTB domain-containing protein 1
    Names
    zmp:0000000868

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      7997913..8039373
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003199567.5 → XP_003199615.1  rho-related BTB domain-containing protein 1

      UniProtKB/TrEMBL
      A0A8M1RSW5, E7FDG6
      Conserved Domains (3) summary
      cd01873
      Location:9 → 203
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      smart00225
      Location:477 → 569
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cl28614
      Location:355 → 446
      BTB; Broad-Complex, Tramtrack and Bric a brac

    2. XM_021480263.1 → XP_021335938.1  rho-related BTB domain-containing protein 1

      UniProtKB/TrEMBL
      A0A8M1RSW5, E7FDG6
      Related
      ENSDARP00000106826.1, ENSDART00000126661.3
      Conserved Domains (3) summary
      cd01873
      Location:9 → 203
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      smart00225
      Location:477 → 569
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cl28614
      Location:355 → 446
      BTB; Broad-Complex, Tramtrack and Bric a brac
    Nucleotide Protein Strain
    Heading Accession and Version

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