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    insrr insulin receptor related receptor [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100490498, updated on 8-Mar-2024

    Summary

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    Official Symbol
    insrrprovided by Xenbase
    Official Full Name
    insulin receptor related receptorprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-483108
    See related
    Ensembl:ENSXETG00000018010
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    irr
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 8
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (131541228..131592340)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (110158083..110205125)

    Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene SH2 domain containing 2A Neighboring gene NIMA-related kinase 2 Neighboring gene neurotrophic receptor tyrosine kinase 1 Neighboring gene platelet endothelial aggregation receptor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables insulin receptor substrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol 3-kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within transmembrane receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    insulin receptor-related protein
    Names
    insulin-related receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      131541228..131592340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004917350.4 → XP_004917407.2  insulin receptor-related protein isoform X1

      UniProtKB/TrEMBL
      A0A6I8SB61
      Related
      ENSXETP00000095545.2, ENSXETT00000067074.2
      Conserved Domains (4) summary
      cd05032
      Location:999 → 1275
      PTKc_InsR_like; Catalytic domain of Insulin Receptor-like Protein Tyrosine Kinases
      cd00063
      Location:837 → 927
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00757
      Location:177 → 330
      Furin-like; Furin-like cysteine rich region
      pfam01030
      Location:350 → 456
      Recep_L_domain; Receptor L domain

    2. XM_002938994.5 → XP_002939040.3  insulin receptor-related protein isoform X2

      UniProtKB/TrEMBL
      A0A8J0QQG4
      Conserved Domains (4) summary
      cd05032
      Location:998 → 1274
      PTKc_InsR_like; Catalytic domain of Insulin Receptor-like Protein Tyrosine Kinases
      cd00063
      Location:837 → 927
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00757
      Location:177 → 330
      Furin-like; Furin-like cysteine rich region
      pfam01030
      Location:350 → 456
      Recep_L_domain; Receptor L domain

    3. XM_004917351.4 → XP_004917408.2  insulin receptor-related protein isoform X3

      UniProtKB/TrEMBL
      A0A6I8SVS8
      Related
      ENSXETP00000097362.2, ENSXETT00000082002.2
      Conserved Domains (4) summary
      cd05032
      Location:985 → 1261
      PTKc_InsR_like; Catalytic domain of Insulin Receptor-like Protein Tyrosine Kinases
      cd00063
      Location:823 → 913
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00757
      Location:177 → 330
      Furin-like; Furin-like cysteine rich region
      pfam01030
      Location:350 → 456
      Recep_L_domain; Receptor L domain
    Nucleotide Protein Strain
    Heading Accession and Version

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