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    DBN1 drebrin 1 [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100434757, updated on 3-Apr-2024

    Summary

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    Gene symbol
    DBN1
    Gene description
    drebrin 1
    Locus tag
    CR201_G0051618
    See related
    Ensembl:ENSPPYG00000016094
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 4 NC_071989.2 (185346278..185362655)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 5 NC_071990.1 (184533252..184549622)

    Chromosome 4 - NC_071989.2Genomic Context describing neighboring genes Neighboring gene PDZ and LIM domain 7 Neighboring gene uncharacterized LOC134761455 Neighboring gene proline rich 7, synaptic Neighboring gene uncharacterized LOC134761456 Neighboring gene G protein-coupled receptor kinase 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neuron projection morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of axon extension IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of dendritic spine morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in postsynaptic actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cortical actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lamellipodium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in site of polarized growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    drebrin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071989.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      185346278..185362655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024247007.3 → XP_024102775.1  drebrin isoform X1

      UniProtKB/TrEMBL
      A0A2J8RDR8, A0A2J8RDV9, A0A8I5TB79
      Related
      ENSPPYP00000033202.1
      Conserved Domains (1) summary
      cd11281
      Location:4 → 139
      ADF_drebrin_like; ADF homology domain of drebrin and actin-binding protein 1 (abp1)

    2. XM_054556284.2 → XP_054412259.1  drebrin isoform X3

    3. XM_054556286.2 → XP_054412261.1  drebrin isoform X6

      UniProtKB/TrEMBL
      A0A2J8RDT3, H2PHI6

    4. XM_024247008.3 → XP_024102776.1  drebrin isoform X2

      UniProtKB/TrEMBL
      A0A2J8RDR8, A0A8I5YMX3
      Related
      ENSPPYP00000027640.1
      Conserved Domains (1) summary
      cd11281
      Location:21 → 134
      ADF_drebrin_like; ADF homology domain of drebrin and actin-binding protein 1 (abp1)

    5. XM_054556285.2 → XP_054412260.1  drebrin isoform X4

      UniProtKB/TrEMBL
      A0A8I5U0P7

    6. XM_024247009.3 → XP_024102777.1  drebrin isoform X5

      UniProtKB/TrEMBL
      A0A2J8RDR8
      Conserved Domains (1) summary
      cl15697
      Location:1 → 76
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    7. XM_054556287.2 → XP_054412262.1  drebrin isoform X5

    Nucleotide Protein
    Heading Accession and Version

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