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    Agtr1 angiotensin II receptor type 1 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100192325, updated on 3-Apr-2024

    Summary

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    Gene symbol
    Agtr1
    Gene description
    angiotensin II receptor type 1
    See related
    Ensembl:ENSCPOG00000007610
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Also known as
    at1
    Orthologs
    human mouse all
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    Genomic context

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    See Agtr1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947488.1 (73643848..73688128)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176411.1 (45454044..45498416)

    NW_026947488.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA synthetase short-chain family member 3, mitochondrial-like Neighboring gene SH2/SH3 adapter protein NCK1-like Neighboring gene carboxypeptidase B1 Neighboring gene carboxypeptidase A3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Angiotensin II type 1 receptor mediates partially hyposmotic-induced increase of I (Ks) current in guinea pig atrium. Zankov DP, et al. Pflugers Arch, 2009 Sep. PMID 19404674
    2. Molecular cloning of guinea pig angiotensin type 1 receptor. Hosoda Y, et al. Biol Signals Recept, 2000 Sep-Oct. PMID 10965057

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables C-C chemokine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables C-C chemokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables angiotensin type II receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in brain development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in calcium-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of vasoconstriction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    type-1 angiotensin II receptor
    Names
    AT1 receptor
    angiotensin II type-1 receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001173046.1 → NP_001166517.1  type-1 angiotensin II receptor

      See identical proteins and their annotated locations for NP_001166517.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ301623
      UniProtKB/TrEMBL
      Q9EPP3
      Conserved Domains (2) summary
      pfam00001
      Location:45 → 302
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      pfam05296
      Location:26 → 224
      TAS2R; Taste receptor protein (TAS2R)

    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947488.1 Reference mCavPor4.1

      Range
      73643848..73688128
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063247904.1 → XP_063103974.1  type-1 angiotensin II receptor isoform X1

      UniProtKB/Swiss-Prot
      Q9WV26

    2. XM_013159551.3 → XP_013015005.1  type-1 angiotensin II receptor isoform X1

      See identical proteins and their annotated locations for XP_013015005.1

      UniProtKB/Swiss-Prot
      Q9WV26
      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    3. XM_023560017.2 → XP_023415785.1  type-1 angiotensin II receptor isoform X1

      UniProtKB/Swiss-Prot
      Q9WV26
      Related
      ENSCPOP00000006858.2
      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    RNA

    1. XR_010047141.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9WV26.1 GenPept UniProtKB/Swiss-Prot:Q9WV26

    Gene LinkOut

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