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    LRP12 LDL receptor related protein 12 [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100173603, updated on 3-Apr-2024

    Summary

    Gene symbol
    LRP12
    Gene description
    LDL receptor related protein 12
    Locus tag
    CR201_G0028307
    See related
    Ensembl:ENSPPYG00000018813
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Also known as
    LRP-12
    Orthologs
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    Genomic context

    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 7 NC_071992.2 (120480751..120597467, complement)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 8 NC_071993.1 (124103814..124213249, complement)

    Chromosome 7 - NC_071992.2Genomic Context describing neighboring genes Neighboring gene dendrocyte expressed seven transmembrane protein Neighboring gene dihydropyrimidinase Neighboring gene uncharacterized LOC112134636 Neighboring gene large ribosomal subunit protein eL29-like Neighboring gene uncharacterized LOC134761871

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Clone Names

    • DKFZp459C0127, DKFZp459F2124

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    low-density lipoprotein receptor-related protein 12
    Names
    low density lipoprotein-related protein 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001133134.1NP_001126606.1  low-density lipoprotein receptor-related protein 12 isoform 1 precursor

      See identical proteins and their annotated locations for NP_001126606.1

      Status: VALIDATED

      Source sequence(s)
      CR860634
      UniProtKB/TrEMBL
      A0A2J8UFU6
      Related
      ENSPPYP00000032230.1, ENSPPYT00000042947.1
      Conserved Domains (2) summary
      cd00041
      Location:47158
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:451485
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    2. NM_001135407.2NP_001128879.1  low-density lipoprotein receptor-related protein 12 isoform 2 precursor

      See identical proteins and their annotated locations for NP_001128879.1

      Status: VALIDATED

      Source sequence(s)
      CR860720
      UniProtKB/TrEMBL
      A0A2J8UFU6
      Related
      ENSPPYP00000021104.3, ENSPPYT00000021947.3
      Conserved Domains (2) summary
      cd00041
      Location:28139
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:432466
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071992.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      120480751..120597467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054560971.2XP_054416946.1  low-density lipoprotein receptor-related protein 12 isoform X1

    RNA

    1. XR_008527657.2 RNA Sequence