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    LPIN3 lipin 3 [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100171775, updated on 10-Apr-2024

    Summary

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    Gene symbol
    LPIN3
    Gene description
    lipin 3
    Locus tag
    CR201_G0018782
    See related
    Ensembl:ENSPPYG00000011013
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 21
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 21 NC_072006.2 (45548447..45568220)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 20 NC_072005.1 (39459297..39479047)

    Chromosome 21 - NC_072006.2Genomic Context describing neighboring genes Neighboring gene zinc fingers and homeoboxes 3 Neighboring gene acireductone dioxygenase-like Neighboring gene uncharacterized LOC129052234 Neighboring gene small nucleolar RNA U3 Neighboring gene elastin microfibril interfacer 3 Neighboring gene uncharacterized LOC129052235 Neighboring gene chromodomain helicase DNA binding protein 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp469D075

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to insulin stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fatty acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in triglyceride biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidate phosphatase LPIN3
    NP_001361253.1
    XP_009231860.2
    XP_024094223.1
    XP_054397368.1
    XP_054397369.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374324.2 → NP_001361253.1  phosphatidate phosphatase LPIN3

      Status: VALIDATED

      Source sequence(s)
      JAQQLQ020000025
      UniProtKB/TrEMBL
      A0A2J8VJZ8
      Conserved Domains (3) summary
      pfam04571
      Location:1 → 106
      Lipin_N; lipin, N-terminal conserved region
      pfam08235
      Location:588 → 813
      LNS2; LNS2 (Lipin/Ned1/Smp2)
      pfam16876
      Location:438 → 528
      Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_072006.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      45548447..45568220
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009233585.4 → XP_009231860.2  phosphatidate phosphatase LPIN3 isoform X1

      UniProtKB/TrEMBL
      A0A2J8VJY1, H2P1Y2
      Related
      ENSPPYP00000012300.3
      Conserved Domains (3) summary
      pfam04571
      Location:1 → 107
      Lipin_N; lipin, N-terminal conserved region
      pfam08235
      Location:589 → 814
      LNS2; LNS2 (Lipin/Ned1/Smp2)
      pfam16876
      Location:439 → 529
      Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

    2. XM_024238455.3 → XP_024094223.1  phosphatidate phosphatase LPIN3 isoform X1

      UniProtKB/TrEMBL
      A0A2J8VJY1, H2P1Y2
      Conserved Domains (3) summary
      pfam04571
      Location:1 → 107
      Lipin_N; lipin, N-terminal conserved region
      pfam08235
      Location:589 → 814
      LNS2; LNS2 (Lipin/Ned1/Smp2)
      pfam16876
      Location:439 → 529
      Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

    3. XM_054541393.2 → XP_054397368.1  phosphatidate phosphatase LPIN3 isoform X2

      UniProtKB/TrEMBL
      A0A2J8VJZ8

    4. XM_054541394.2 → XP_054397369.1  phosphatidate phosphatase LPIN3 isoform X3

    RNA

    1. XR_008516782.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001131435.1: Suppressed sequence

      Description
      NM_001131435.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version

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