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    VIPR1 vasoactive intestinal peptide receptor 1 [ Sus scrofa (pig) ]

    Gene ID: 100155402, updated on 8-Mar-2024

    Summary

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    Official Symbol
    VIPR1provided by VGNC
    Official Full Name
    vasoactive intestinal peptide receptor 1provided by VGNC
    Primary source
    VGNC:VGNC:94827
    See related
    Ensembl:ENSSSCG00000011280
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    VPAC1; VIP-R-1; PACAP-R2; PACAP-R-2
    Expression
    Broad expression in lung (RPKM 7.4), liver (RPKM 2.1) and 6 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See VIPR1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (26036610..26073168)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (28704211..28740358)

    Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110256272 Neighboring gene lysozyme like 4 Neighboring gene SEC22 homolog C, vesicle trafficking protein Neighboring gene SS18 like 2 Neighboring gene natural killer cell triggering receptor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Expression of VPAC1 receptor at the level of mRNA and protein in the porcine female reproductive system. Bukowski R, et al. Pol J Vet Sci, 2015. PMID 25928928
    2. Alterations in the relative abundance of the vasoactive intestinal peptide receptors (VPAC1 and VPAC2) and functions in uterine contractility during inflammation. Palus K, et al. Anim Reprod Sci, 2021 Feb. PMID 33388613

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Alterations in the relative abundance of the vasoactive intestinal peptide receptors (VPAC1 and VPAC2) and functions in uterine contractility during inflammation.
      Title: Alterations in the relative abundance of the vasoactive intestinal peptide receptors (VPAC1 and VPAC2) and functions in uterine contractility during inflammation.
    2. The study confirmed the presence of VPAC1 receptor in the tissues of the porcine female reproductive tract what clearly shows the possibility of influence of vasoactive intestinal polypeptide on the porcine ovary, oviduct and uterus.
      Title: Expression of VPAC1 receptor at the level of mRNA and protein in the porcine female reproductive system.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled peptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peptide hormone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables vasoactive intestinal polypeptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vasoactive intestinal polypeptide receptor 1
    Names
    PACAP type II receptor
    pituitary adenylate cyclase-activating polypeptide type II receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214036.1 → NP_999201.1  vasoactive intestinal polypeptide receptor 1 precursor

      See identical proteins and their annotated locations for NP_999201.1

      Status: PROVISIONAL

      Source sequence(s)
      U49434
      UniProtKB/Swiss-Prot
      Q28992
      UniProtKB/TrEMBL
      A0A8D0MD10
      Related
      ENSSSCP00000059376.1, ENSSSCT00000050683.2
      Conserved Domains (2) summary
      smart00008
      Location:60 → 130
      HormR; Domain present in hormone receptors
      pfam00002
      Location:140 → 385
      7tm_2; 7 transmembrane receptor (Secretin family)

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

      Range
      26036610..26073168
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005669395.3 → XP_005669452.1  vasoactive intestinal polypeptide receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A287BT69, A0A4X1TLS1
      Conserved Domains (2) summary
      smart00008
      Location:60 → 130
      HormR; Domain present in hormone receptors
      pfam00002
      Location:141 → 386
      7tm_2; 7 transmembrane receptor (Secretin family)

    2. XM_021068243.1 → XP_020923902.1  vasoactive intestinal polypeptide receptor 1 isoform X6

      UniProtKB/TrEMBL
      A0A4X1TLT2, A0A8D0MEX4
      Related
      ENSSSCP00000012026.4, ENSSSCT00000012349.4
      Conserved Domains (3) summary
      smart00008
      Location:1 → 64
      HormR; Domain present in hormone receptors
      cd14964
      Location:77 → 101
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:74 → 340
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_013981508.2 → XP_013836962.1  vasoactive intestinal polypeptide receptor 1 isoform X3

      UniProtKB/TrEMBL
      A0A4X1TLQ5, A0A8D0W5H6, A0A8D1CW64, D9IWC2
      Related
      ENSSSCP00000042733.1, ENSSSCT00000038088.1
      Conserved Domains (2) summary
      smart00008
      Location:18 → 88
      HormR; Domain present in hormone receptors
      pfam00002
      Location:98 → 343
      7tm_2; 7 transmembrane receptor (Secretin family)

    4. XM_013981510.2 → XP_013836964.1  vasoactive intestinal polypeptide receptor 1 isoform X7

      UniProtKB/TrEMBL
      A0A4X1TLQ0, D9IWC0, D9IWC4
      Conserved Domains (1) summary
      cl21561
      Location:1 → 114
      7tm_4; Olfactory receptor

    5. XM_005669397.3 → XP_005669454.1  vasoactive intestinal polypeptide receptor 1 isoform X5

      See identical proteins and their annotated locations for XP_005669454.1

      UniProtKB/TrEMBL
      A0A8D0MEX4, D9IWB9, F1SRG8
      Conserved Domains (2) summary
      smart00008
      Location:1 → 64
      HormR; Domain present in hormone receptors
      pfam00002
      Location:75 → 320
      7tm_2; 7 transmembrane receptor (Secretin family)

    6. XM_013981507.2 → XP_013836961.1  vasoactive intestinal polypeptide receptor 1 isoform X2

      UniProtKB/TrEMBL
      A0A8D1ZHU2
      Conserved Domains (2) summary
      smart00008
      Location:18 → 88
      HormR; Domain present in hormone receptors
      pfam00002
      Location:99 → 344
      7tm_2; 7 transmembrane receptor (Secretin family)

    7. XM_021068242.1 → XP_020923901.1  vasoactive intestinal polypeptide receptor 1 isoform X4

      UniProtKB/TrEMBL
      A0A8D1ZBD6
      Conserved Domains (3) summary
      smart00008
      Location:6 → 74
      HormR; Domain present in hormone receptors
      cd14964
      Location:88 → 112
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:85 → 351
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28992.1 GenPept UniProtKB/Swiss-Prot:Q28992

    Gene LinkOut

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