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    Por P450 (cytochrome) oxidoreductase [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100135602, updated on 3-Apr-2024

    Summary

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    Gene symbol
    Por
    Gene description
    P450 (cytochrome) oxidoreductase
    See related
    Ensembl:ENSCPOG00000006202
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947506.1 (41867392..41918947, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176389.1 (1599723..1651185)

    NW_026947506.1Genomic Context describing neighboring genes Neighboring gene serine/threonine/tyrosine interacting like 1 Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene transmembrane protein 120A Neighboring gene uncharacterized LOC134472514 Neighboring gene uracil-DNA glycosylase-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and sequence analysis of guinea-pig NADPH-cytochrome P-450 oxidoreductase. Ohgiya S, et al. Biochim Biophys Acta, 1993 Sep 23. PMID 8373812
    2. Mouse NADPH-cytochrome P-450 oxidoreductase: molecular cloning and functional expression in yeast. Ohgiya S, et al. Biochim Biophys Acta, 1994 Jun 28. PMID 8011664
    3. Molecular cloning and sequence analysis of guinea-pig NADPH-cytochrome P-450 oxidoreductase [corrected]. Ohgiya S, et al. Biochim Biophys Acta, 1992 Nov 15. PMID 1420354

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables NADPH-hemoprotein reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADPH--cytochrome P450 reductase
    Names
    CPR
    NADPH-cytochrome P450 oxidoreductase
    P450R
    NP_001166473.1
    XP_013007952.2
    XP_063089582.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001173002.1 → NP_001166473.1  NADPH--cytochrome P450 reductase

      See identical proteins and their annotated locations for NP_001166473.1

      Status: PROVISIONAL

      Source sequence(s)
      D10498
      UniProtKB/Swiss-Prot
      P37039
      UniProtKB/TrEMBL
      H0V790
      Conserved Domains (3) summary
      cd06204
      Location:277 → 677
      CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
      COG0369
      Location:52 → 677
      CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
      pfam00258
      Location:82 → 219
      Flavodoxin_1; Flavodoxin

    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947506.1 Reference mCavPor4.1

      Range
      41867392..41918947 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013152498.3 → XP_013007952.2  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/Swiss-Prot
      P37039

    2. XM_063233512.1 → XP_063089582.1  NADPH--cytochrome P450 reductase isoform X2

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P37039.2 GenPept UniProtKB/Swiss-Prot:P37039

    Gene LinkOut

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