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    ctsf cathepsin F [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100127591, updated on 8-Mar-2024

    Summary

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    Official Symbol
    ctsfprovided by Xenbase
    Official Full Name
    cathepsin Fprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-5876529
    See related
    Ensembl:ENSXETG00000017109
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (39623333..39668715, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (42244906..42264583, complement)

    Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116410365 Neighboring gene uncharacterized LOC116410367 Neighboring gene uncharacterized LOC116410366 Neighboring gene pyruvate carboxylase, gene 2 Neighboring gene leucine rich repeat and fibronectin type III domain containing 4 Neighboring gene phosphofurin acidic cluster sorting protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cathepsin F
    NP_001106423.1
    XP_031755638.1
    XP_031755639.1
    XP_031755640.1
    XP_031755641.1
    XP_031755642.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001112952.1 → NP_001106423.1  cathepsin F precursor

      See identical proteins and their annotated locations for NP_001106423.1

      Status: PROVISIONAL

      Source sequence(s)
      BC153363
      UniProtKB/TrEMBL
      A0A6I8PLE6, A8E4X3
      Related
      ENSXETP00000059094.3, ENSXETT00000061497.3
      Conserved Domains (3) summary
      smart00043
      Location:23 → 130
      CY; Cystatin-like domain
      smart00848
      Location:166 → 222
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:250 → 461
      Peptidase_C1; Papain family cysteine protease

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      39623333..39668715 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031899781.1 → XP_031755641.1  cathepsin F isoform X4

      UniProtKB/TrEMBL
      A0A6I8PLE6, A0A8J1JG66
      Conserved Domains (3) summary
      smart00848
      Location:114 → 170
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:198 → 409
      Peptidase_C1; Papain family cysteine protease
      cl09238
      Location:16 → 78
      CY; Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.

    2. XM_031899782.1 → XP_031755642.1  cathepsin F isoform X4

      UniProtKB/TrEMBL
      A0A6I8PLE6, A0A8J1JG66
      Conserved Domains (3) summary
      smart00848
      Location:114 → 170
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:198 → 409
      Peptidase_C1; Papain family cysteine protease
      cl09238
      Location:16 → 78
      CY; Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.

    3. XM_031899779.1 → XP_031755639.1  cathepsin F isoform X2

      UniProtKB/TrEMBL
      A0A803J8N3, F7ECR2
      Related
      ENSXETP00000104235.1, ENSXETT00000120025.1
      Conserved Domains (3) summary
      smart00043
      Location:20 → 127
      CY; Cystatin-like domain
      smart00848
      Location:163 → 219
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:247 → 458
      Peptidase_C1; Papain family cysteine protease

    4. XM_031899780.1 → XP_031755640.1  cathepsin F isoform X3

      UniProtKB/TrEMBL
      A0A6I8PLE6, A0A6I8R0X4
      Related
      ENSXETP00000113098.1, ENSXETT00000123046.1
      Conserved Domains (3) summary
      smart00043
      Location:8 → 115
      CY; Cystatin-like domain
      smart00848
      Location:151 → 207
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:235 → 446
      Peptidase_C1; Papain family cysteine protease

    5. XM_031899778.1 → XP_031755638.1  cathepsin F isoform X1

      UniProtKB/TrEMBL
      A0A6I8PLE6, A8E4X3
      Conserved Domains (3) summary
      smart00043
      Location:23 → 130
      CY; Cystatin-like domain
      smart00848
      Location:166 → 222
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:250 → 461
      Peptidase_C1; Papain family cysteine protease
    Nucleotide Protein Strain
    Heading Accession and Version

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